2023

Wing, P.A., Schmidt, N.M., Peters, R., Erdmann, M., Brown, R., Wang, H., ...Thakur, N. (2023). An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity. PLoS Pathogens, 19 (5), doi:10.1371/journal.ppat.1011323
Swadling, L., Maini, M.K. (2023). Can T Cells Abort SARS-CoV-2 and Other Viral Infections?. International Journal of Molecular Sciences, 24 (5), doi:10.3390/ijms24054371
Peters, M.G., Yuen, M.-.F., Terrault, N., Fry, J., Lampertico, P., Gane, E., ...Maini, M.K. (2023). Chronic Hepatitis B Finite Treatment: similar and different concerns with new drug classes. Clinical Infectious Diseases, doi:10.1093/cid/ciad506
Maini, M.K. (2023). EASL International Recognition Award Recipient 2023: Prof. Antonio Bertoletti. JOURNAL OF HEPATOLOGY, 79 (1), 10-12. doi:10.1016/j.jhep.2023.03.033
Bertoletti, A., Le Bert, N., Tan, A.T., Boni, C., Fisicaro, P., Ferrari, C., ...Maini, M. (2023). End-of-treatment HBcrAg and HBsAb levels identify durable functional cure after Peg-IFN-based therapy in patients with CHB, by Huang et al. J Hepatology 77, 42-54 (2022).. Journal of Hepatology, S0168-8278(23)00408. doi:10.1016/j.jhep.2023.05.032
Barreby, E., Strunz, B., Nock, S., Naudet, L., Shen, J.X., Johansson, H., ...Pallett, L.J. (2023). Human resident liver myeloid cells protect against metabolic stress in obesity. Nature Metabolism, doi:10.1038/s42255-023-00834-7
Milighetti, M., Peng, Y., Tan, C., Mark, M., Nageswaran, G., Byrne, S., ...Chandran, A. (2023). Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection. iScience, 26 (6), doi:10.1016/j.isci.2023.106937
Dusheiko, G., Agarwal, K., Maini, M.K. (2023). New Approaches to Chronic Hepatitis B. New England Journal of Medicine, 388 55-69. doi:10.1056/NEJMra2211764
Dusheiko, G., Agarwal, K., Maini, M.K. (2023). New Approaches to Chronic Hepatitis B [Correspondence: author reply]. New England Journal of Medicine, 388 (12), 1148. doi:10.1056/NEJMc2301248
Altmann, D.M., Reynolds, C.J., Joy, G., Otter, A.D., Gibbons, J.M., Pade, C., ...Semper, A. (2023). Persistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity. Nature Communications, 14 (1), doi:10.1038/s41467-023-40460-1
Diniz, M.O., Maini, M.K., Swadling, L. (2023). T cell control of SARS-CoV-2: When, which, and where?. Seminars in Immunology, 70 doi:10.1016/j.smim.2023.101828
Lim, S.G., Baumert, T.F., Boni, C., Gane, E., Levrero, M., Lok, A.S., ...Zoulim, F. (2023). The scientific basis of combination therapy for chronic hepatitis B functional cure. Nature Reviews Gastroenterology and Hepatology, doi:10.1038/s41575-022-00724-5
Pallett, L.J., Swadling, L., Diniz, M., Maini, A.A., Schwabenland, M., Gasull, A.D., ...Thomas, N. (2023). Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS.. Nature, doi:10.1038/s41586-022-05645-6

2022

Kramvis, A., Chang, K.-.M., Dandri, M., Farci, P., Glebe, D., Hu, J., ...Pollicino, T. (2022). A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook.. Nature Reviews Gastroenterology and Hepatology, doi:10.1038/s41575-022-00649-z
Maini, M., Diniz, M., Mitsi, E., Swadling, L., Rylance, J., Ferreira, D. (2022). Airway-resident functional T cell responses against SARS-CoV-2 in unexposed individuals. .
Diniz, M.O., Mitsi, E., Swadling, L., Rylance, J., Johnson, M., Goldblatt, D., ...Maini, M.K. (2022). Airway-resident T cells from unexposed individuals cross-recognize SARS-CoV-2. Nature Immunology, doi:10.1038/s41590-022-01292-1
Pallett, L.J., Diniz, M., Swadling, L., Skelton, J., Maini, A., Davies, J., ...Gill, U. (2022). CD8+T cell acquisition of the LPS receptor within the hepatic stroma shapes anti-viral/anti-tumour potential.
Zakeri, N., Hall, A., Swadling, L., Pallett, L.J., Schmidt, N.M., Diniz, M.O., ...Pinzani, M. (2022). Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma. Nature Communications, 13 doi:10.1038/s41467-022-29012-1
Lens, S., Burton, A., Davies, J., Garcia-Lopez, M., Jeffery-Smith, A., Novikov, N., ...Maini, M. (2022). Differential changes in global and antigen-specific B cell frequencies and function associate with the outcome of HBV nucleos (t)ide analog treatment withdrawal.
Reuschl, A.-.K., Mesner, D., Shivkumar, M., Whelan, M.V.X., Pallett, L.J., Guerra-Assunção, J.A., ...Thornhill, J.P. (2022). HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells. Cell Reports, 39 (2), doi:10.1016/j.celrep.2022.110650
Astbury, S., Reynolds, C.J., Butler, D.K., Munoz-Sandoval, D.C., Lin, K.-.M., Pieper, F.P., ...Nightingale, J. (2022). HLA-DR polymorphism in SARS-CoV-2 infection and susceptibility to symptomatic COVID-19. Immunology, doi:10.1111/imm.13450
Reynolds, C.J., Pade, C., Gibbons, J.M., Otter, A.D., Lin, K.-.M., Muñoz Sandoval, D., ...Joy, G. (2022). Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure. Science, doi:10.1126/science.abq1841
Walker, A., Schwarz, T., Brinkmann-Paulukat, J., Wisskirchen, K., Menne, C., Alizei, E.S., ...zur Wiesch, J.S. (2022). Immune escape pathways from the HBV core(18-27) CD8 T cell response are driven by individual HLA class I alleles. Frontiers in Immunology, 13 doi:10.3389/fimmu.2022.1045498
Gehring, A.J., Mendez, P., Richter, K., Ertl, H., Donaldson, E.F., Mishra, P., ...de Creus, A. (2022). Immunological Biomarker Discovery in Cure Regimens for Chronic Hepatitis B Virus Infection.. Journal of Hepatology, doi:10.1016/j.jhep.2022.02.020
Kucykowicz, S., Amin, O.E., Burton, A.R., Swadling, L., Schmidt, N.M., Zakeri, N., ...Easom, N.J. (2022). Isolation of human intrahepatic leukocytes for phenotypic and functional characterization by flow cytometry. STAR Protocols, 3 (2), doi:10.1016/j.xpro.2022.101356
Pallett, L.J., Maini, M.K. (2022). Liver-resident memory T cells: life in lockdown. Seminars in Immunopathology, doi:10.1007/s00281-022-00932-w
Garcia-Lopez, M., Pallett, L.J., Rodriguez-Tajes, S., Belmonte, E., Leonel, T., Garcia-Pras, E., ...Rando-Segura, A. (2022). Liver-resident T cell PD-1 correlates with intrahepatic HBV-DNA and is reduced following prolonged antiviral therapy.
Diniz, M.O., Schurich, A., Chinnakannan, S.K., Duriez, M., Stegmann, K.A., Davies, J., ...Alcock, F. (2022). NK cells limit therapeutic vaccine-induced CD8+T cell immunity in a PD-L1-dependent manner.. Science Translational Medicine, 14 (640), eabi4670. doi:10.1126/scitranslmed.abi4670
Altmann, D., Reynolds, C., Joy, G., Otter, A., Gibbons, J., Pade, C., ...Semper, A. (2022). Persistent symptoms after COVID-19 during the first wave are not associated with differential immunity to SARS-CoV-2.
Captur, G., Moon, J.C., Topriceanu, C.-.C., Joy, G., Swadling, L., Hallqvist, J., ...Baldwin, T. (2022). Plasma proteomic signature predicts who will get persistent symptoms following SARS-CoV-2 infection. eBioMedicine, doi:10.1016/j.ebiom.2022.104293
Singh, K.P., Pallett, L.J., Singh, H., Chen, A., Otano, I., Duriez, M., ...Fusai, G. (2022). Pro-fibrogenic role of alarmin HMGB1 in HIV-HBV co-infection.. AIDS, doi:10.1097/QAD.0000000000003435
Doykov, I., Baldwin, T., Spiewak, J., Gilmour, K.C., Gibbons, J.M., Pade, C., ...Maini, M.K. (2022). Quantitative, multiplexed, targeted proteomics for ascertaining variant specific SARS-CoV-2 antibody response.. Cell Reports Methods, 100279. doi:10.1016/j.crmeth.2022.100279
Chandran, A., Rosenheim, J., Nageswaran, G., Swadling, L., Pollara, G., Gupta, R.K., ...Ronel, T. (2022). Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections. Cell Reports Medicine, doi:10.1016/j.xcrm.2022.100557
Maini, M.K., Diniz, M.O. (2022). SARS-CoV-2-cross-reactive T cells identified in pre-pandemic lower airway samples. Nature Immunology, 23 (9), 1307-1308. doi:10.1038/s41590-022-01308-w
Balloux, F., Tan, C., Swadling, L., Richard, D., Jenner, C., Maini, M., van Dorp, L. (2022). The past, current and future epidemiological dynamic of SARS-CoV-2. Oxford Open Immunology, 3 (1), doi:10.1093/oxfimm/iqac003

2021

Zakeri, N., Hall, A., Swadling, L., Pallett, L.J., Schmidt, N.M., Diniz, M.O., ...Pinzani, M. (2021). AMINOBISPHOSPHONATES ENHANCE LIVER-RESIDENT GAMMA DELTA T CELLS FOR EFFICIENT TARGETING OF HEPATOCELLULAR CARCINOMA.
Gupta, R.K., Rosenheim, J., Bell, L.C., Chandran, A., Guerra-Assuncao, J.A., Pollara, G., ...Kurdi, H. (2021). Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study. The Lancet Microbe, 2 e508-e517.
Cossarizza, A., Chang, H.D., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., ...Arranz, E. (2021). Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition). European Journal of Immunology, doi:10.1002/eji.202170126
Zakeri, N., Swadling, L., Pallett, L.J., Schmidt, N.M., Diniz, M.O., Kucykowicz, S., ...Davidson, B.R. (2021). Harnessing liver-resident gamma delta T cells for immunotherapy of hepatocellular carcinoma.
Reynolds, C.J., Gibbons, J.M., Pade, C., Lin, K.-.M., Sandoval, D.M., Pieper, F., ...Joy, G. (2021). Heterologous infection and vaccination shapes immunity against SARS-CoV-2 variants.. Science, eabm0811. doi:10.1126/science.abm0811
Reuschl, A.-.K., Shivkumar, M., Mesner, D., Pallett, L., Guerra-Assunção, J.A., Madansein, R., ...Herrera, C. (2021). HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells. .
Burton, A.R., Maini, M.K. (2021). Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID-19.. Immunol Rev, doi:10.1111/imr.12953
Llovet, J.M., Castet, F., Heikenwalder, M., Maini, M.K., Mazzaferro, V., Pinato, D.J., ...Finn, R.S. (2021). Immunotherapies for hepatocellular carcinoma. Nature Reviews Clinical Oncology, doi:10.1038/s41571-021-00573-2
Yang, H., Llano, A., Cedeño, S., von Delft, A., Corcuera, A., Gillespie, G.M., ...Stöhr, W. (2021). Incoming HIV virion-derived Gag Spacer Peptide 2 (p1) is a target of effective CD8+ T cell antiviral responses.. Cell Reports, 35 (6), 109103. doi:10.1016/j.celrep.2021.109103
Zakeri, N., Hall, A., Swadling, L., Pallett, L.J., Schmidt, N.M., Diniz, M.O., ...Davidson, B.R. (2021). Liver-resident gamma delta T cells are long-lived and can be induced to target hepatocellular carcinoma.
Swadling, L., Diniz, M.O., Schmidt, N.M., Amin, O.E., Chandran, A., Shaw, E., ...Tan, A.T. (2021). Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2. Nature, doi:10.1038/s41586-021-04186-8
Swadling, L., Diniz, M., Schmidt, N., Amin, O., Chandran, A., Shaw, E., ...Tan, A. (2021). Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 infection. .
Reynolds, C.J., Pade, C., Gibbons, J.M., Butler, D.K., Otter, A.D., Menacho, K., ...Cutino-Moguel, T. (2021). Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose. Science,
Jeffery-Smith, A., Burton, A.R., Lens, S., Rees-Spear, C., Davies, J., Patel, M., ...Doores, K.J. (2021). SARS-CoV-2-specific memory B cells can persist in the elderly who have lost detectable neutralising antibodies.. Journal of Clinical Investigation, doi:10.1172/JCI152042
Lens, S., Heiberg, I., Winther, T.N., Jeffery-Smith, A., Novikov, N., Fletcher, S., ...Maini, M. (2021). Selective depletion of HBsAg-specific B cells in paediatric HBV infection.
Schmidt, N.M., Wing, P.A.C., Diniz, M.O., Pallett, L.J., Swadling, L., Harris, J.M., ...Amin, O.E. (2021). Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.. Nature Communications, 12 (1), 2814. doi:10.1038/s41467-021-22967-7
Wiggins, B.G., Pallett, L.J., Li, X., Davies, S.P., Amin, O.E., Gill, U.S., ...Liu, Y.S. (2021). The human liver microenvironment shapes the homing and function of CD4+ T-cell populations. Gut, doi:10.1136/gutjnl-2020-323771
de Silva, T.I., Liu, G., Lindsey, B.B., Dong, D., Moore, S.C., Hsu, N.S., ...Angyal, A. (2021). The impact of viral mutations on recognition by SARS-CoV-2 specific T cells. iScience, 24 (11), doi:10.1016/j.isci.2021.103353
Manisty, C., Treibel, T.A., Jensen, M., Semper, A., Joy, G., Gupta, R.K., ...Taylor, S. (2021). Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection.. EBioMedicine, 65 103259. doi:10.1016/j.ebiom.2021.103259

2020

Fidler, S., Stöhr, W., Pace, M., Dorrell, L., Lever, A., Pett, S., ...Nelson, M. (2020). Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial.. Lancet, doi:10.1016/S0140-6736(19)32990-3
Schmidt, N.M., Wing, P.A.C., McKeating, J.A., Maini, M.K. (2020). Cholesterol-modifying drugs in COVID-19. Oxford Open Immunology, 1 (1), doi:10.1093/oxfimm/iqaa001
Perpiñán, E., Pérez-Del-Pulgar, S., Londoño, M.-.C., Mariño, Z., Bartres, C., González, P., ...Maini, M.K. (2020). Cirrhosis Hampers Early and Rapid Normalization of Natural Killer Cell Phenotype and Function in Hepatitis C Patients Undergoing Interferon-Free Therapy.. Front Immunol, 11 129. doi:10.3389/fimmu.2020.00129
Preece, R., Pavesi, A., Gkazi, S.A., Stegmann, K.A., Georgiadis, C., Tan, Z.M., ...Qasim, W. (2020). CRISPR mediated base conversion allows discriminatory depletion of endogenous T cell receptors for enhanced synthetic immunity. Molecular Therapy - Methods & Clinical Development, doi:10.1016/j.omtm.2020.09.002
Reynolds, C.J., Swadling, L., Gibbons, J.M., Pade, C., Jensen, M.P., Diniz, M.O., ...Bailey, S.N.L. (2020). Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection. Science immunology, 5 eabf3698.
Cornberg, M., Lok, A.S.F., Terrault, N.A., Zoulim, F., Berg, T., Brunetto, M.R., ...Chang, K.M. (2020). Guidance for Design and Endpoints of Clinical Trials in Chronic Hepatitis B—Report From the 2019 EASL-AASLD HBV Treatment Endpoints Conference. Hepatology, 71 (3), 1070-1092. doi:10.1002/hep.31030
Swadling, L., Pallett, L.J., Diniz, M.O., Baker, J.M., Amin, O.E., Stegmann, K.A., ...Zakeri, N. (2020). Human Liver Memory CD8⁺ T Cells Use Autophagy for Tissue Residence.. Cell Reports, 30 (3), 687-698.e6. doi:10.1016/j.celrep.2019.12.050
Hague, R.M., Hine, D., Fergusson, J., Wallace, Z., Woon, A., Kay, D., ...Suckling, R. (2020). Immtav, a novel immunotherapy approach to eliminate hepatitis B virus.
Fergusson, J.R., Wallace, Z., Connolly, M.M., Woon, A.P., Suckling, R.J., Hine, D.W., ...Crespillo, S. (2020). Immune-Mobilizing Monoclonal T Cell Receptors Mediate Specific and Rapid Elimination of Hepatitis B-Infected Cells. HEPATOLOGY, 72 (5), 1528-1540. doi:10.1002/hep.31503
Swadling, L., Pallett, L.J., Maini, M.K. (2020). Liver-resident CD8+ T cells: learning lessons from the local experts. Journal of Hepatology, doi:10.1016/j.jhep.2020.02.001
Pallett, L.J., Burton, A.R., Amin, O.E., Rodriguez-Tajes, S., Patel, A.A., Zakeri, N., ...Baiges, A. (2020). Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes. The Journal of Experimental Medicine, 217 (9), doi:10.1084/jem.20200050
Gkazi, S.-.A., Preece, R., Pavesi, A., Stegmann, K., Georgiadis, C., Tan, D., ...Qasim, W. (2020). Recombinant T Cell Receptor Immunity Against Hepatitis B Surface Antigen Following Disruptive Base Editing of Endogenous T Cell Receptor.
Garcia-Lopez, M., Lens, S., Pallett, L.J., Testoni, B., Marino, Z., Rodriguez-Tajes, S., ...Perpinan, E. (2020). Serum and intrahepatic HBV markers and HBV-specific CD8 T cell responses after nucleos(t)ide analog therapy discontinuation in HBeAg-negative chronic hepatitis B patients.
Pereira, B., De Maeyer, R., Covre, L., Nehar-Belaid, D., Lanna, A., Ward, S., ...Riddell, N. (2020). Sestrins induce natural killer function in senescent-like CD8+ T cells. Nature Immunology, doi:10.1038/s41590-020-0643-3
Maini, M.K., Peppa, D. (2020). Shared immunotherapeutic approaches in HIV and hepatitis B virus: combine and conquer.. Curr Opin HIV AIDS, 15 (3), 157-164. doi:10.1097/COH.0000000000000621
Swadling, L., Maini, M.K. (2020). T cells in COVID-19 — united in diversity. Nature Immunology, doi:10.1038/s41590-020-0798-y
Chinnakannan, S.K., Cargill, T.N., Donnison, T.A., Ansari, M.A., Sebastian, S., Lee, L.N., ...Evans, T. (2020). The design and development of a multi-HBV antigen encoded in chimpanzee adenoviral and modified vaccinia ankara viral vectors; a novel therapeutic vaccine strategy against HBV. Vaccines, 8 (2), doi:10.3390/vaccines8020184
Amin, O.E., Colbeck, E.J., Daffis, S., Khan, S., Ramakrishnan, D., Pattabiraman, D., ...Peiser, L. (2020). Therapeutic potential of TLR8 agonist GS-9688 (selgantolimod) in chronic hepatitis B: re-modelling of antiviral and regulatory mediators.. Hepatology, doi:10.1002/hep.31695
Easom, N.J.W., Marks, M., Jobe, D., Gillmore, R., Meyer, T., Maini, M.K., Njie, R. (2020). ULBP1 Is Elevated in Human Hepatocellular Carcinoma and Predicts Outcome. Frontiers in Oncology, 10 doi:10.3389/fonc.2020.00971
García-López, M., Lens, S., Pallett, L.J., Testoni, B., Rodríguez-Tajes, S., Mariño, Z., ...Perpiñán, E. (2020). Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients.. J Hepatol, doi:10.1016/j.jhep.2020.11.043

2019

Revill, P.A., Chisari, F.V., Block, J.M., Dandri, M., Gehring, A.J., Guo, H., ...Janssen, H.L.A. (2019). A global scientific strategy to cure hepatitis B. The Lancet Gastroenterology & Hepatology, 4 (7), 545-558. doi:10.1016/S2468-1253(19)30119-0
Maini, M.K. (2019). CD8+ T cells cure without killing.. Nat Rev Immunol, doi:10.1038/s41577-019-0150-7
Gill, U.S., Le Bert, N., Kunasegaran, K., Hansi, N., Tan, D., Peppa, D., ...Kennedy, P.T.F. (2019). GENE ONTOLOGY ENRICHMENT AND INGENUITY PATHWAY ANALYSIS REVEALS DIFFERENTIALLY IMMUNE REGULATED NETWORKS IN TREATED COMPARED TO UNTREATED CHRONIC HEPATITIS B PATIENTS..
Cornberg, M., Lok, A.S.F., Terrault, N.A., Zoulim, F., Berg, T., Brunetto, M.R., ...Chang, K.M. (2019). Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference‡. Journal of Hepatology, doi:10.1016/j.jhep.2019.11.003
Amin, O.E., Colbeck, E., Daffis, S., Pattabiraman, D., Sitali, C., Rosenberg, W., ...Pallett, L.J. (2019). In vitro modulation by TLR8 agonist GS-9688 of multiple regulatory cell types in patients with chronic hepatitis B.
Pallett, L.J., Burton, A., Amin, O.E., Zakeri, N., Thorburn, D., Yona, S., Maini, M. (2019). Liver-resident HBV-specific CD8+T cells are long-lived and can be replenished by allogenic responses following transplantation.
Rodriguez-Tajes, S., Pallett, L.J., Garcia-Lopez, M., Baiges, A., Perpinan, E., Lens, S., ...Carlos Garcia-Pagan, J. (2019). Liver-resident memory CD8 T cells do not egress into hepatic venous blood.
Schwenzer, H., Jühling, F., Chu, A., Pallett, L.J., Baumert, T.F., Maini, M., Fassati, A. (2019). Oxidative Stress Triggers Selective tRNA Retrograde Transport in Human Cells during the Integrated Stress Response. Cell Reports, 26 (12), 3416-3428.e5. doi:10.1016/j.celrep.2019.02.077
Cargill, T., Donnison, T., Ansari, A., Maini, M., Evans, T., Barnes, E., Chinnakannan, S.K. (2019). Prime-boost vaccination strategies using chimpanzee-adeno and MVA viral vectored vaccines encoding multiple HBV antigens (CPmutS) and class II invariant chain molecular adjuvants induces robust T-cell and anti-HBs antibody response in mice.
Maini, M.K., Burton, A.R. (2019). Restoring, releasing or replacing adaptive immunity in chronic hepatitis B. Nature Reviews Gastroenterology & Hepatology, doi:10.1038/s41575-019-0196-9

2018

Chinnakannan, S.K., Cargill, T., Donnison, T., Ansari, A., Maini, M., Evans, T., Barnes, E. (2018). A novel chimpanzee adenoviral vectored HBV vaccine, encoding multiple HBV antigens with a shark invariant chain adjuvant, for use in HBV immunotherapy.
Peppa, D., Pedroza-Pacheco, I., Pellegrino, P., Williams, I., Maini, M.K., Borrow, P. (2018). Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection. FRONTIERS IN IMMUNOLOGY, 9 doi:10.3389/fimmu.2018.00474
Burton, A.R., Pallett, L.J., McCoy, L.E., Suveizdyte, K., Amin, O.E., Swadling, L., ...Gill, U.S. (2018). Circulating and intrahepatic antiviral B cells are defective in hepatitis B.. J Clin Invest, doi:10.1172/JCI121960
Maini, M.K., Pallett, L.J. (2018). Defective T-cell immunity in hepatitis B virus infection: why therapeutic vaccination needs a helping hand.. The lancet. Gastroenterology & hepatology, 3 (3), 192-202. doi:10.1016/s2468-1253(18)30007-4
Burton, A., Pallett, L.J., Mccoy, L., Suveizdyte, K., Amin, O.E., Froghi, F., ...Mauri, C. (2018). Dysfunctional surface antigen-specific memory B cells accumulate in chronic hepatitis B infection.
Gill, U.S., Pallett, L.J., Thomas, N., Burton, A.R., Patel, A.A., Yona, S., ...Maini, M.K. (2018). Fine needle aspirates comprehensively sample intrahepatic immunity.. Gut, doi:10.1136/gutjnl-2018-317071
Gill, U.S., Hansi, N., Bert, N.L., Kunasegaran, K., Dolman, G.E., Tan, D., ...Kennedy, P. (2018). HBV-specific T cell responses in low replicating inactive carrier patients are independent of Hepatitis B surface antigen load.
Laing, N., Tufton, H., Ochola, E., P'Kingston, O.G., Maini, M.K., Easom, N. (2018). Hepatitis B assessment without hepatitis B virus DNA quantification: a prospective cohort study in Uganda.. Trans R Soc Trop Med Hyg, doi:10.1093/trstmh/try117
Easom, N.J.W., Stegmann, K.A., Swadling, L., Pallett, L.J., Burton, A.R., Odera, D., ...Davidson, B. (2018). IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction. FRONTIERS IN IMMUNOLOGY, 9 doi:10.3389/fimmu.2018.01009
Gill, U.S., Pallett, L.J., Kennedy, P.T.F., Maini, M.K. (2018). Liver sampling: a vital window into HBV pathogenesis on the path to functional cure.. Gut, doi:10.1136/gutjnl-2017-314873
Otano, I., Escors, D., Schurich, A., Singh, H., Robertson, F., Davidson, B.R., ...Aw, J.Y.J. (2018). Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver. Molecular Therapy, doi:10.1016/j.ymthe.2018.08.013
Perpinan, E., del Pulgar, S.P., Londono, M.C., Marino, Z., Lens, S., Bartres, C., ...Pose, E. (2018). Normalization of NK cell phenotype is delayed after successful interferon-free therapy in cirrhotic patients with chronic HCV infection.
Gill, U.S., Pallett, L.J., Burton, A., Stegmann, K., Kennedy, P., Maini, M. (2018). Probing new HBV therapies using fine needle aspirates to sample compartmentalised liver-resident immunity and hepatocytes.
Gill, U.S., Pallett, L.J., Thomas, N., Burton, A.R., Stegmann, K.A., Kennedy, P.T.F., Maini, M.K. (2018). Probing Novel HBV Therapies Using Fine Needle Aspirates to Sample Compartmentalised Liver-Resident Immunity and Hepatocytes.
Schmidt, N., Pallett, L.J., Schurich, A., Suveizdyte, K., Amin, O.E., Froghi, F., ...Rosenberg, W. (2018). Rescuing hepatitis-B-specific T cell responses by modulating cholesterol metabolism.
Khakpoor, A., Ni, Y., Chen, A., Ho, Z.Z., Oei, V., Yang, N., ...Kennedy, P.T. (2018). Spatio-temporal differences in presentation of CD8 T cell epitopes during HBV infection.. J Virol, doi:10.1128/JVI.01457-18

2017

Duriez, M., Mandouri, Y., Lekbaby, B., Wang, H., Schnuriger, A., Redelsperger, F., ...Ahodantin, J. (2017). Alternative splicing of hepatitis B virus: A novel virus/host interaction altering liver immunity.. Journal of hepatology, doi:10.1016/j.jhep.2017.05.025
Gill, U.S., Peppa, D., Micco, L., Singh, H.D., Le Bert, N., Rivino, L., ...Maini, M.K. (2017). Effect of in-vivo hepatitis B viral load suppression after interferon exposure on natural killer and T-cell responsiveness.
Maini, M.K., Bertoletti, A. (2017). HBV in 2016: Global and immunotherapeutic insights into hepatitis B. Nature Reviews Gastroenterology & Hepatology, 14 (2), 71-72. doi:10.1038/nrgastro.2016.196
Pallett, L.J., Davies, J., Colbeck, E.J., Robertson, F., Hansi, N., Easom, N.J.W., ...Swadling, L. (2017). IL-2high tissue-resident T cells in the human liver: Sentinels for hepatotropic infection.. The Journal of experimental medicine, 214 (6), 1567-1580. doi:10.1084/jem.20162115
Male, V., Stegmann, K.A., Easom, N.J., Maini, M.K. (2017). Natural Killer Cells in Liver Disease. SEMINARS IN LIVER DISEASE, 37 (3), 198-209. doi:10.1055/s-0037-1603946
Huang, W.C., Easom, N.J., Tang, X.Z., Gill, U.S., Singh, H., Robertson, F., ...Rosenberg, W.M. (2017). T Cells Infiltrating Diseased Liver Express Ligands for the NKG2D Stress Surveillance System.. J Immunol, doi:10.4049/jimmunol.1601313
Singh, H.D., Otano, I., Rombouts, K., Singh, K.P., Peppa, D., Gill, U.S., ...Pinzani, M. (2017). TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis. SCIENTIFIC REPORTS, 7 doi:10.1038/s41598-017-05845-5
Gill, U.S., Bert, N.L., Kunasegaran, K., Khakpoor, A., Hansi, N., Tan, D., ...Peppa, D. (2017). Transcriptome profiles of NK and T cells associated with immune control in chronic hepatitis B patients treated with pegylated interferon alpha-nucleos(t)ide analogue sequential therapy.

2016

Di Scala, M., Otano, I., Gil-Farina, I., Vanrell, L., Hommel, M., Olague, C., ...Ortiz de Solorzano, C. (2016). Complementary Effects of Interleukin-15 and Alpha Interferon Induce Immunity in Hepatitis B Virus Transgenic Mice. JOURNAL OF VIROLOGY, 90 (19), 8563-8574. doi:10.1128/JVI.01030-16
Stegmann, K.A., Robertson, F., Hansi, N., Gill, U., Pallant, C., Christophides, T., ...Fusai, G. (2016). CXCR6 marks a novel subset of T-bet(lo)Eomes(hi) natural killer cells residing in human liver. SCIENTIFIC REPORTS, 6 doi:10.1038/srep26157
Schurich, A., Pallett, L.J., Jajbhay, D., Wijngaarden, J., Otano, I., Gill, U.S., ...Gilson, R. (2016). Distinct Metabolic Requirements of Exhausted and Functional Virus-Specific CD8 T Cells in the Same Host.. Cell reports, doi:10.1016/j.celrep.2016.06.078
Male, V., Cuff, A.O., Robertson, F.P., Stegmann, K.A., Pallett, L.J., Maini, M.K., Davidson, B.R. (2016). Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation. Journal of Immunology, doi:10.4049/jimmunol.1601424
Otano, I., Arce, F., Singh, H., Schurich, A., Peppa, D., Gilson, R., ...Maini, M.K. (2016). GENETICALLY ENGINEERING HBV-SPECIFIC CD8+T CELLS RESISTANT TO TRAIL-MEDIATED APOPTOSIS.
Rickinson, A., Easom, N., Maini, M., Rowe, M. (2016). Immunity to Oncogenic Viruses. In Encyclopedia of Immunobiology. (pp. 363-374). .
Gill, U.S., Peppa, D., Micco, L., Singh, H.D., Carey, I., Foster, G.R., ...Kennedy, P.T. (2016). Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.. PLoS pathogens, 12 (8), e1005788.
Maini, M.K., Gehring, A.J. (2016). The role of innate immunity in the immunopathology and treatment of HBV infection.. Journal of hepatology, 64 (1 Suppl), S60-S70.

2015

Easom, N., Laing, N., Tufton, H., Ochola, E., Elliot, A., Maini, M. (2015). ASSESSMENT OF THE EFFECTIVENESS AND UTILITY OF THE NEW WHO GUIDELINES FOR THE MANAGEMENT OF HEPATITIS B IN NORTHERN UGANDA.
Heiberg, I.L., Pallett, L.J., Winther, T.N., Høgh, B., Maini, M.K., Peppa, D. (2015). Defective natural killer cell anti-viral capacity in paediatric HBV infection.. Clin Exp Immunol, 179 (3), 466-476. doi:10.1111/cei.12470
Davidson, S., Maini, M.K., Wack, A. (2015). Disease-Promoting Effects of Type I Interferons in Viral, Bacterial, and Coinfections. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 35 (4), 252-264. doi:10.1089/jir.2014.0227
Qasim, W., Brunetto, M., Gehring, A.J., Xue, S.-.A., Schurich, A., Khakpoor, A., ...Cavallone, D. (2015). Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient.. JOURNAL OF HEPATOLOGY, 62 (2), 486-491. doi:10.1016/j.jhep.2014.10.001
Pallett, L.J., Gill, U.S., Quaglia, A., Sinclair, L.V., Jover-Cobos, M., Schurich, A., ...Chen, A. (2015). Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells. Nature Medicine, 21 (6), 591-600. doi:10.1038/nm.3856
Lampertico, P., Maini, M., Papatheodoridis, G. (2015). Optimal management of hepatitis B virus infection - EASL Special Conference. JOURNAL OF HEPATOLOGY, 63 (5), 1238-1253. doi:10.1016/j.jhep.2015.06.026
Qasim, W., Brunetto, M., Gehring, A.J., Maini, M.K., Bonino, F., Stauss, H., Bertoletti, A. (2015). Reply to: "To target or not to target viral antigens in HBV related HCC?''. JOURNAL OF HEPATOLOGY, 62 (6), 1450-1452. doi:10.1016/j.jhep.2015.02.026
Arenas-Pinto, A., Milinkovic, A., Peppa, D., McKendry, A., Maini, M., Gilson, R. (2015). Systemic inflammation and residual viraemia in HIV-positive adults on protease inhibitor monotherapy: a cross-sectional study.. BMC Infect Dis, 15 (1), doi:10.1186/s12879-015-0889-9
Bertoletti, A., Brunetto, M., Maini, M.K., Bonino, F., Qasim, W., Stauss, H. (2015). T cell receptor-therapy in HBV-related hepatocellularcarcinoma. ONCOIMMUNOLOGY, 4 (6), doi:10.1080/2162402X.2015.1008354

2014

Maini, M.K., Schurich, A. (2014). Direct-acting antivirals trump interferon-alpha in their capacity to rescue exhausted T cells upon HCV clearance.. JOURNAL OF HEPATOLOGY, 61 (3), 459-461. doi:10.1016/j.jhep.2014.06.017
Macdonald, D.C., Singh, H., Whelan, M.A., Escors, D., Arce, F., Bottoms, S.E., ...Rosenberg, W.M.C. (2014). Harnessing alveolar macrophages for sustained mucosal T-cell recall confers long-term protection to mice against lethal influenza challenge without clinical disease.. MUCOSAL IMMUNOLOGY, 7 (1), 89-100. doi:10.1038/mi.2013.27
Gill, U.S., Peppa, D., Micco, L., Singh, H.D., Foster, G., Maini, M., Kennedy, P.T. (2014). Sequential Nuc Therapy Following Pegylated Interferon-Alpha Exposure Restores Innate Immune Responses Conferring a Treatment Advantage Over Nuc Monotherapy in Chronic Hepatitis B.

2013

Micco, L., Peppa, D., Loggi, E., Schurich, A., Jefferson, L., Cursaro, C., ...Bihl, F. (2013). Differential boosting of innate and adaptive antiviral responses during pegylated-interferon-alpha therapy of chronic hepatitis B.. JOURNAL OF HEPATOLOGY, 58 (2), 225-233. doi:10.1016/j.jhep.2012.09.029
Maini, M.K., Peppa, D. (2013). NK cells: a double-edged sword in chronic hepatitis B virus infection.. Front Immunol, 4 doi:10.3389/fimmu.2013.00057
Schurich, A., Pallett, L.J., Lubowiecki, M., Singh, H.D., Gill, U.S., Kennedy, P.T., ...Maini, M.K. (2013). The third signal cytokine IL-12 rescues the anti-viral function of exhausted HBV-specific CD8 T cells.. PLoS Pathogens, 9 (3), doi:10.1371/journal.ppat.1003208
Peppa, D., Gill, U.S., Reynolds, G., Easom, N.J.W., Pallett, L.J., Schurich, A., ...Adams, D.H. (2013). Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion.. JOURNAL OF EXPERIMENTAL MEDICINE, 210 (1), 99-114. doi:10.1084/jem.20121172

2012

Nebbia, G., Peppa, D., Maini, M.K. (2012). Hepatitis B infection: current concepts and future challenges.. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 105 (2), 109-113. doi:10.1093/qjmed/hcr270
Das, A., Ellis, G., Pallant, C., Lopes, A.R., Khanna, P., Peppa, D., ...Gill, U. (2012). IL-10-producing regulatory B cells in the pathogenesis of chronic hepatitis B virus infection.. JOURNAL OF IMMUNOLOGY, 189 (8), 3925-3935. doi:10.4049/jimmunol.1103139
Liu, M., Miao, T., Zhu, H., Symonds, A.L.J., Li, L., Schurich, A., ...Li, S. (2012). IL-2-engineered nano-APC effectively activates viral antigen-mediated T cell responses from chronic hepatitis B virus-infected patients. Journal of Immunology, 188 (3), 1534-1543. doi:10.4049/jimmunol.1102709
Liu, M., Miao, T., Zhu, H., Symonds, A.L.J., Li, L., Schurich, A., ...Li, S. (2012). IL-2-engineered nano-APC effectively activates viral antigen-mediated T cell responses from chronic hepatitis B virus-infected patients.. JOURNAL OF IMMUNOLOGY, 188 (3), 1534-1543. doi:10.4049/jimmunol.1102709
Protzer, U., Maini, M.K., Knolle, P.A. (2012). Living in the liver: hepatic infections.. NATURE REVIEWS IMMUNOLOGY, 12 (3), 201-213. doi:10.1038/nri3169
Peppa, D., Maini, M.K. (2012). Pathogenesis of hepatitis B virus infection and potential for new therapies.. BRITISH JOURNAL OF HOSPITAL MEDICINE, 73 (10), 581-584. doi:10.12968/hmed.2012.73.10.581
Maini, M.K., Schurich, A. (2012). Platelets harness the immune response to drive liver cancer.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109 (32), 12840-12841. doi:10.1073/pnas.1210296109
Zhao, Q., Peng, L., Huang, W., Li, Q., Pei, Y., Yuan, P., ...Zhong, C. (2012). Rare inborn errors associated with chronic hepatitis B virus infection.. HEPATOLOGY, 56 (5), 1661-1670. doi:10.1002/hep.25850
Nebbia, G., Peppa, D., Schurich, A., Khanna, P., Singh, H.D., Cheng, Y., ...ChinAleong, J. (2012). Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection.. PLOS One, 7 (10), doi:10.1371/journal.pone.0047648

2011

Gehring, A.J., Xue, S.A., Ho, Z.Z., Teoh, D., Ruedl, C., Chia, A., ...Stauss, H. (2011). Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines. Journal of Hepatology, 55 (1), 103-110. doi:10.1016/j.jhep.2010.10.025
Gehring, A.J., Xue, S.-.A., Ho, Z.Z., Teoh, D., Ruedl, C., Chia, A., ...Stauss, H. (2011). Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines.. JOURNAL OF HEPATOLOGY, 55 (1), 103-110. doi:10.1016/j.jhep.2010.10.025
Gehring, A.J., Koh, S., Chia, A., Paramasivam, K., Chew, V.S.P., Ho, Z.Z., ...Lim, S.G. (2011). Licensing virus-specific T cells to secrete the neutrophil attracting chemokine CXCL-8 during hepatitis B virus infection.. PLOS ONE, 6 (8), doi:10.1371/journal.pone.0023330
Micco, L., Peppa, D., Loggi, E., Schurich, A., Carmela, C., Panno, A.M., ...Maini, M.K. (2011). PEGYLATED INTERFERON-ALPHA POTENTLY AUGMENTS NK CELL ANTIVIRAL EFFECTOR FUNCTION.
Schurich, A., Khanna, P., Lopes, A.R., Han, K.J., Peppa, D., Micco, L., ...Dusheiko, G. (2011). Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection.. HEPATOLOGY, 53 (5), 1494-1503. doi:10.1002/hep.24249

2010

Peppa, D., Micco, L., Javaid, A., Kennedy, P.T.F., Schurich, A., Dunn, C., ...Dusheiko, G. (2010). Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection.. PLOS PATHOG, 6 (12), doi:10.1371/journal.ppat.1001227
Hoare, M., Gelson, W.T.H., Das, A., Fletcher, J.M., Davies, S.E., Curran, M.D., ...Alexander, G.J.M. (2010). CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infection. J Hepatol., 53 (2), 252-260.
Das, A., Maini, M.K. (2010). Innate and adaptive immune responses in hepatitis B virus infection.. DIGESTIVE DISEASES, 28 (1), 126-132. doi:10.1159/000282075
Bertoletti, A., Maini, M.K., Ferrari, C. (2010). The host-pathogen interaction during HBV infection: immunological controversies. ANTIVIRAL THERAPY, 15 15-24. doi:10.3851/IMP1620
Maini, M.K., Schurich, A. (2010). The molecular basis of the failed immune response in chronic HBV: therapeutic implications.. JOURNAL OF HEPATOLOGY, 52 (4), 616-619. doi:10.1016/j.jhep.2009.12.017

2009

Dunn, C., Peppa, D., Khanna, P., Nebbia, G., Jones, M., Brendish, N., ...Tedder, R.J. (2009). Temporal analysis of early immune responses in patients with acute hepatitis B virus infection.. Gastroenterology, 137 (4), 1289-1300. doi:10.1053/j.gastro.2009.06.054

2008

Lopes, A.R., Kellam, P., Das, A., Dunn, C., Kwan, A., Turner, J., ...Bertoletti, A. (2008). Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection. Journal of Clinical Investigation, 118 (5), 1835-1845. doi:10.1172/JCI33402
Das, A., Hoare, M., Davies, N., Lopes, A.R., Dunn, C., Kennedy, T.F., ...Plunkett, F.J. (2008). Functional Skewing of the global CD8 T cell population in chronic hepatitis B virus infection. Journal of Experimental Medicine, 205 2111-2124.

2007

Dunn, C., Brunetto, M., Reynolds, G., Christophides, T., Kennedy, P.T., Lampertico, P., ...Williams, K. (2007). Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage. Journal of Experimental Medicine, 204 (3), 667-680. doi:10.1084/jem.20061287
Gehring, A.J., Sun, D., Kennedy, P.T., Nolte-'t, H.E., Lim, S.G., Wasser, S., ...Nassal, M. (2007). The level of viral antigen presented by hepatocytes influences CD8 T-cell function. J Virol., 81 (6), 2940-2949.
Gehring, A.J., Sun, D., Kennedy, P.T.F., Nolte-'T Hoen, E., Lim, S.G., Wasser, S., ...Nassal, M. (2007). The level of viral antigen presented by hepatocytes influences CD8 T-cell function. Journal of Virology, 81 (6), 2940-2949. doi:10.1128/JVI.02415-06

2006

Turnbull, E.L., Lopes, A.R., Jones, N.A., Cornforth, D., Newton, P., Aldam, D., ...Wilson, C.M. (2006). HIV-1 epitope-specific CD8+ T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently. The Journal of Immunology, 176 (10), 6130-6146.
Kennedy, P.T.F., Urbani, S., Moses, R.A., Amadei, B., Fisicaro, P., Lloyd, J., ...Bertoletti, A. (2006). The Influence of T Cell Cross-Reactivity on HCVPeptide Specific Human T Cell Response.. Hepatology, 43 602-611.

2005

Lascar, R.M., Lopes, A.R., Gilson, R.J., Dunn, C., Johnstone, R., Copas, A., ...Maini, M.K. (2005). Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection. The Journal of Infectious Diseases, 191 (7), 1169-1179. doi:10.1086/428502
Franzese, O., Kennedy, P.T.F., Gehring, A.J., Gotto, J., Williams, R., Maini, M.K., Bertoletti, A. (2005). Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with hepatitis B virus infection.. JOURNAL OF VIROLOGY, 79 (6), 3322-3328. doi:10.1128/JVI.79.6.3322-3328.2005
Maini, M.K., Bertoletti, A. (2005). The effects of pathogens on the immune system: viral hepatitis.. In Frelinger, J.A. (Ed.), Immunodominance: The choice of the immune system. Wiley-VCH.

2003

Lopes, A.R., Jaye, A., Dorrell, L., Sabally, S., Alabi, A., Jones, N.A., ...Lascar, R.M. (2003). Greater CD8+ TCR heterogeneity and functional flexibility in HIV-2 compared to HIV-1 infection. The Journal of Immunology, 171 (1), 307-316.
Lascar, R.M., Gilson, R.J.C., Lopes, A.R., Bertoletti, A., Maini, M.K. (2003). Reconstitution of hepatitis B virus (HBV)-specific T cell responses with treatment of human immunodeficiency virus/HBV coinfection. The Journal of Infectious Diseases, 188 (12), 1815-1819. doi:10.1086/379896
Bertoletti, A., Maini, M., Williams, R. (2003). Role of hepatitis B virus specific cytotoxic T cells in liver damage and viral control. Antiviral Research, 60 (2), 61-66.
Bertoletti, A., Maini, M., Williams, R. (2003). Role of hepatitis B virus specific cytotoxic T cells in liver damage and viral control. ANTIVIRAL RESEARCH, 60 (2), 61-66. doi:10.1016/j.antiviral.2003.08.012

2002

Maini, M.K., Bertoletti, A. (2002). Cytokines in viral hepatitis. In Kobt, M., Calandra, T. (Eds.), Cytokines and chemokines in infectious diseases. (pp. 355-375). Humana Press.
Reignat, S., Webster, G.J.M., Brown, D., Ogg, G.S., Williams, R., Maini, M.K., Bertoletti, A. (2002). Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus (HBV) infection. Journal of Experimental Medicine, 195 1089-1101. doi:10.1084/jem.20011723
Reignat, S., Webster, G.J., Brown, D., Ogg, G.S., King, A., Seneviratne, S.L., ...Bertoletti, A. (2002). Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection. Journal of Experimental Medicine, 195 (9), 1089-1101. doi:10.1084/jem.20011723

2000

Maini, M.K., Gudgeon, N., Wedderburn, L.R., Rickinson, A.B., Beverley, P.C. (2000). Clonal expansions in acute EBV infection are detectable in the CD8 and not the CD4 subset and persist with a variable CD45 phenotype. The Journal of Immunology, 165 (10), 5729-5737.
Beverley, P.C.L., Maini, M.K. (2000). Differences in the regulation of CD4 and CD8 T-cell clones during immune responses.
Beverley, P.C., Maini, M.K. (2000). Differences in the regulation of CD4 and CD8 T-cell clones during immune responses. Philosophical Transactions of the Royal Society B: Biological Sciences, 355 (1395), 401-406. doi:10.1098/rstb.2000.0580
Maini, M.K., Bertoletti, A. (2000). How can the cellular immune response control hepatitis B virus replication?. Journal of Viral Hepatitis, 7 (5), 321-326.
Webster, G.J., Reignat, S., Maini, M.K., Whalley, S.A., Ogg, G.S., King, A., ...Vergani, D. (2000). Incubation phase of acute hepatitis B in man: dynamic of cellular immune mechanisms. Hepatology, 32 (5), 1117-1124.
Bertoletti, A., Maini, M.K. (2000). Protection or damage: a dual role for the virus-specific cytotoxic T lymphocyte response in hepatitis B and C infection?. Current Opinion in Immunology, 12 (4), 403-408.
Bertoletti, A., Maini, M.K. (2000). Protection or damage: a dual role for the virus-specific cytotoxic T lymphocyte response in hepatitis B and C infection?. CURRENT OPINION IN MICROBIOLOGY, 3 (4), 387-392. doi:10.1016/S1369-5274(00)00109-0
Soares, M.V.D., Maini, M.K., Beverley, P.C.L., Salmon, M., Akbar, A.N. (2000). Regulation of apoptosis and replicative senescence in CD8+ T cells from patients with viral infections. Biochemical Society Transactions, 28 (Part 2), 255-258.
Maini, M.K., Reignat, S., Boni, C., Ogg, G.S., King, A.S., Malacarne, F., ...Bertoletti, A. (2000). T cell receptor usage of virus-specific CD8 cells and recognition of viral mutations during acute and persistent hepatitis B virus infection. European Journal of Immunology, 30 (11), 3067-3078.
Maini, M.K., Boni, C., Lee, C.K., Larrubia, J.R., Reignat, S., Ogg, G.S., ...Alisa, A. (2000). The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection. Journal of Experimental Medicine, 191 (8), 1269-1280. doi:10.1084/jem.191.8.1269

1999

Maini, M.K., Boni, C., Ogg, G.S., King, A.S., Reignat, S., Lee, C.K., ...Ferrari, C. (1999). Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection. GASTROENTEROLOGY, 117 (6), 1386-1396.
Maini, M.K., Boni, C., Ogg, G.S., King, A.S., Reignat, S., Lee, C.K., ...Ferrari, C. (1999). Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection.. GASTROENTEROLOGY, 117 (6), 1386-1396. doi:10.1016/S0016-5085(99)70289-1
Wedderburn, L.R., Maini, M.K., Patel, A., Beverley, P.C., Woo, P. (1999). Molecular fingerprinting reveals non-overlapping T cell oligoclonality between an inflamed site and peripheral blood. Int.Immunol., 11 (4), 535-543.
Wedderburn, L.R., Maini, M.K., Patel, A., Beverley, P.C.L., Woo, P. (1999). Molecular fingerprinting reveals non-overlapping T cell oligoclonality between an inflamed site and peripheral blood. International Immunology, 11 (4), 535-543.
Maini, M.K., Casorati, G., Dellabona, P., Wack, A., Beverley, P.C. (1999). T-cell clonality in immune responses. Immunology Today, 20 (6), 262-266. doi:10.1016/S0167-5699(99)01472-3
Maini, M.K., Casorati, G., Dellabona, P., Wack, A., Beverley, P.C.L. (1999). T-cell clonality in immune responses. IMMUNOLOGY TODAY, 20 (6), 262-266. doi:10.1016/S0167-5699(99)01472-3
Maini, M.K., Soares, M.V.D., Zilch, C.F., Akbar, A.N., Beverley, P.C.L. (1999). Virus-induced CD8(+) T cell clonal expansion is associated with telomerase up-regulation and telomere length preservation: A mechanism for rescue from replicative senescence. JOURNAL OF IMMUNOLOGY, 162 (8), 4521-4526.

1998

Maini, M.K., Wedderburn, L.R., Hall, F.C., Wack, A., Casorati, G., Beverley, P.C.L. (1998). Comparison of two techniques for the molecular tracking of specific T-cell responses; CD4(+) human T-cell clones persist in a stable hierarchy but at a lower frequency than clones in the CD8(+) population. IMMUNOLOGY, 94 (4), 529-535.
Soares, M.V.D., Borthwick, N.J., Maini, M.K., Janossy, G., Salmon, M., Akbar, A.N. (1998). Interleukin-7 dependent extrarhythmic expansion of CD45RA + T cells enables preservation of a naive repertoire. The Journal of Immunology, 161 5909-5917.

1996

Maini, N.K., Gilson, R.J., Chavda, N., Gill, S., Fakoya, A., Ross, E.J., ...Weller, I.V.D. (1996). Reference ranges and sources of variability of CD4 counts in HIV-seronegative women and men. Genitourinary Medicine, 72 (1), 27-31. doi:10.1136/sti.72.1.27

1994

Robinson, P., Zakrzewska, J.M., Maini, M., Williamson, D., Croucher, R. (1994). Dental visiting behaviour and experiences of men with HIV. British Dental Journal, 176 (5), 175-179.

1992

Maini, M., French, P., Prince, M., Bingham, J.S. (1992). Urethritis due to Neisseria meningitidis in a London genitourinary medicine clinic population. International Journal of STD and AIDS, 3 423-425.

1991

Davidson, R.N., Croft, S.L., Scott, A., Maini, M., Moody, A.H., Bryceson, A.D. (1991). Liposomal amphotericin B in drug-resistant visceral leishmaniasis. The Lancet, 337 1061-1062.

1900

Maini, M. (1900). Clonal dynamics and turnover in T cell memory.
Macdonald, D. (1900). Lentiviral vector vaccines for T cell-mediated protection against influenza. (Doctoral Dissertation). University College London.
Pallett, L. (1900). Metabolic regulation of hepatic immunopathology by myeloid-derived suppressor cells. (Doctoral Dissertation). University College London.
Huang, W.C. (1900). NKG2D-dependent cross talk between NK cells and CD4 T cells in chronic hepatitis B. (Doctoral Dissertation). University College London.