2019

Baruteau, J., Waddington, S.N. (2019). Fetal gene therapy for neurodegenerative lysosomal storage diseases.. J Inherit Metab Dis, doi:10.1002/jimd.12018
Almeida-Porada, G., Waddington, S.N., Chan, J.K.Y., Peranteau, W.H., MacKenzie, T., Porada, C.D. (2019). In Utero Gene Therapy Consensus Statement from the IFeTIS. Molecular Therapy, doi:10.1016/j.ymthe.2019.02.015
Suff, N., Karda, R., Antinao-Diaz, J., Buckley, S.M., Waddington, S.N., Peebles, D.M. (2019). Intrauterine Infection is Associated with a Reduced NFKB Response in Murine Neonatal Developing Brains..
Suff, N., Karda, R., Antinao-Diaz, J., Buckley, S.M., Waddington, S.N., Peebles, D.M. (2019). Intrauterine Infection is Associated with a Reduced NFKB Response in Murine Neonatal Developing Brains..
Al-Allaf, F.A., Abduljaleel, Z., Athar, M., Taher, M.M., Khan, W., Mehmet, H., ...Waddington, S. (2019). Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia. Non-coding RNA Research, 4 (1), 1-14. doi:10.1016/j.ncrna.2018.11.005
Karda, R., Counsell, J.R., Karbowniczek, K., Caproni, L.J., Tite, J.P., Waddington, N. (2019). Production of lentiviral vectors using novel, enzymatically-produced, linear DNA vectors. Gene Ther, doi:10.1038/s41434-018-0056-1

2018

Dighe, N.M., Tan, K.W., Tan, L.G., Shaw, S.S.W., Buckley, S.M.K., Sandikin, D., ...Choolani, M. (2018). A comparison of intrauterine haemopoietic cell transplantation and lentiviral gene transfer for the correction of severe β-thalassaemia in a HbbTh3/+ murine model.. Experimental hematology, doi:10.1016/j.exphem.2018.03.006
Dighe, N.M., Tan, K.W., Tan, L.G., Shaw, S.S.W., Buckley, S.M.K., Sandikin, D., ...Choolani, M. (2018). A comparison of intrauterine haemopoietic cell transplantation and lentiviral gene transfer for the correction of severe β-thalassaemia in a HbbTh3/+ murine model.. Experimental hematology, doi:10.1016/j.exphem.2018.03.006
Tordo, J., O'Leary, C., Antunes, A.S.L.M., Palomar, N., Aldrin-Kirk, P., Basche, M., ...Godwin, A. (2018). A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency.. Brain : a journal of neurology, doi:10.1093/brain/awy126
Diaz, J.F.A., Counsell, J.R., Morris, G., Buckley, S.M.K., Davidge, J., Schorge, S., ...Karda, R. (2018). AAV Gene Therapy for Inherited Childhood Epilepsy, Dravet Syndrome.
Diaz, J.F.A., Counsell, J.R., Morris, G., Buckley, S.M.K., Davidge, J., Schorge, S., ...Karda, R. (2018). AAV Gene Therapy for Inherited Childhood Epilepsy, Dravet Syndrome.
Hughes, M.P., Smith, D.A., Morris, L., Fletcher, C., Colaco, A., Huebecker, M., ...Henckaerts, E. (2018). AAV9 Intracerebroventricular Gene Therapy Improves Lifespan and Normalises Long-Term Locomotor Behaviour in a Mouse Model of Niemann-Pick Type C1 Disease.
Hughes, M.P., Smith, D.A., Morris, L., Fletcher, C., Colaco, A., Huebecker, M., ...Henckaerts, E. (2018). AAV9 intracerebroventricular gene therapy improves lifespan, locomotor function and pathology in a mouse model of Niemann-Pick type C1 disease. Human molecular genetics, doi:10.1093/hmg/ddy212
Perocheau, D., Cunningham, S., Lee, J., Antinao Diaz, J., Waddington, S.N., Gilmour, K., ...Alexander, I.E. (2018). Age-related seroprevalence of antibodies against AAV-LK03 in a UK population cohort.. Human gene therapy, doi:10.1089/hum.2018.098
Baruteau, J., Perocheau, D.P., Hanley, J., Lorvellec, M., Rocha-Ferreira, E., Karda, R., ...Rahim, A.A. (2018). Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by As/ gene transfer. NATURE COMMUNICATIONS, 9 doi:10.1038/s41467-018-05972-1
Baruteau, J., Perocheau, D.P., Hanley, J., Lorvellec, M., Rocha-Ferreira, E., Karda, R., ...Rahim, A.A. (2018). Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by As/ gene transfer. NATURE COMMUNICATIONS, 9 doi:10.1038/s41467-018-05972-1
Suff, N., Karda, R., Antinao Diaz, J., Ng, J., Baruteau, J., Perocheau, D., ...Buckley, S.M.K. (2018). Ascending Vaginal Infection Using Bioluminescent Bacteria Evokes Intrauterine Inflammation, Preterm Birth, and Neonatal Brain Injury in Pregnant Mice. American Journal of Pathology, doi:10.1016/j.ajpath.2018.06.016
Suff, N., Karda, R., Antinao Diaz, J., Ng, J., Baruteau, J., Perocheau, D., ...Buckley, S.M.K. (2018). Ascending Vaginal Infection Using Bioluminescent Bacteria Evokes Intrauterine Inflammation, Preterm Birth, and Neonatal Brain Injury in Pregnant Mice. American Journal of Pathology, doi:10.1016/j.ajpath.2018.06.016
Suff, N., Karda, R., Ng, J., Perocheau, D., Bajaj-Elliott, M., Buckley, S.M.K., ...Peebles, D. (2018). Cervical Gene Delivery of Human Beta-Defensin-3 (HBD-3) Reduces E. coli K1 Ascending Infection and Increases the Proportion of Live Births in Pregnant Mice..
Suff, N., Karda, R., Ng, J., Perocheau, D., Bajaj-Elliott, M., Buckley, S.M.K., ...Peebles, D. (2018). Cervical Gene Delivery of Human Beta-Defensin-3 (HBD-3) Reduces E. coli K1 Ascending Infection and Increases the Proportion of Live Births in Pregnant Mice..
Massaro, G., Mattar, C., Wong, A., Sirka, E., Buckley, S., Herbert, B., ...Heales, S. (2018). Fetal gene therapy for neurodegenerative disease of infants. Nature Medicine, doi:10.1038/s41591-018-0106-7
Massaro, G., Mattar, C., Wong, A., Sirka, E., Buckley, S., Herbert, B., ...Heales, S. (2018). Fetal gene therapy for neurodegenerative disease of infants. Nature Medicine, doi:10.1038/s41591-018-0106-7
Counsell, J.R., Karda, R., Diaz, J.A., Carey, L., Wiktorowicz, T., Buckley, S.M.K., ...Almeida, F. (2018). Foamy Virus Vectors Transduce Visceral Organs and Hippocampal Structures following In Vivo Delivery to Neonatal Mice. Molecular Therapy - Nucleic Acids, 12 626-634. doi:10.1016/j.omtn.2018.07.006
Counsell, J.R., Karda, R., Diaz, J.A., Carey, L., Wiktorowicz, T., Buckley, S.M.K., ...Almeida, F. (2018). Foamy Virus Vectors Transduce Visceral Organs and Hippocampal Structures following In Vivo Delivery to Neonatal Mice. Molecular Therapy - Nucleic Acids, 12 626-634. doi:10.1016/j.omtn.2018.07.006
Karda, R., Rahim, A.A., Suff, N., Diaz, J.A., Perocheau, D.P., Martin, N.P., ...Henckaerts, E. (2018). Generation of Light-Producing Somatic-Transgenic Mice Using Adeno-Associated Virus Vector.
Karda, R., Rahim, A.A., Suff, N., Diaz, J.A., Perocheau, D.P., Martin, N.P., ...Henckaerts, E. (2018). Generation of Light-Producing Somatic-Transgenic Mice Using Adeno-Associated Virus Vector.
FitzPatrick, L.M., Hawkins, K.E., Delhove, J.M.K.M., Fernandez, E., Soldati, C., Bullen, L.F., ...Bolaños, J.P. (2018). NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program. Stem Cell Reports, doi:10.1016/j.stemcr.2018.03.015
Motherwell, W.B., Zard, S.Z. (2018). Preface. PERGAMON-ELSEVIER SCIENCE LTD.
Edey, L.F., Georgiou, H., O'Dea, K.P., Mesiano, S., Herbert, B.R., Lei, K., ...MacIntyre, D. (2018). Progesterone, the maternal immune system and the onset of parturition in the mouse.. Biology of Reproduction, doi:10.1093/biolre/iox146
Chan, J.K.Y., Gil-Farina, I., Johana, N., Rosales, C., Tan, Y.W., Ceiler, J., ...Schmidt, M. (2018). Therapeutic expression of human clotting factors IX and X following adeno-associated viral vector-mediated intrauterine gene transfer in early-gestation fetal macaques.. FASEB Journal, fj201801391R. doi:10.1096/fj.201801391R

2017

Suff, N., Karda, R., Buckley, S.M.K., Tangney, M., Waddington, S.N., Peebles, D., Peebles, D. (2017). A Light-Producing Mouse Model of Ascending Vaginal Infection-Related Preterm Birth..
Suff, N., Karda, R., Buckley, S.M.K., Tangney, M., Waddington, S.N., Peebles, D., Peebles, D. (2017). A Light-Producing Mouse Model of Ascending Vaginal Infection-Related Preterm Birth..
Delhove, J.M.K.M., Karda, R., Hawkins, K.E., FitzPatrick, L.M., Waddington, S.N., McKay, T.R. (2017). Bioluminescence Monitoring of Promoter Activity In Vitro and In Vivo.. In (pp. 49-64). .
Suff, N., Karda, R., Bajaj-Elliott, M., Tangney, M., Ward, T.H., Peebles, D., ...Waddington, S.N. (2017). Cervical gene delivery of human beta-defensin 3 prevents ascending infection in pregnant mice.
Suff, N., Karda, R., Bajaj-Elliott, M., Tangney, M., Ward, T.H., Peebles, D., ...Waddington, S.N. (2017). Cervical gene delivery of human beta-defensin 3 prevents ascending infection in pregnant mice.
Suff, N., Karda, R., Bajaj-Elliott, M., Buckley, S.M.K., Tangney, M., Waddington, S.N., Peebles, D. (2017). Cervical Gene Delivery of Human Beta-Defensin-3(HBD-3) Prevents Ascending Bacterial Infection in Pregnant Mice..
Suff, N., Karda, R., Bajaj-Elliott, M., Buckley, S.M.K., Tangney, M., Waddington, S.N., Peebles, D. (2017). Cervical Gene Delivery of Human Beta-Defensin-3(HBD-3) Prevents Ascending Bacterial Infection in Pregnant Mice..
Ahmed, S.G., Waddington, S.N., Boza-Moran, M.G., Yanez-Munoz, R.J. (2017). Complete Transduction of Spinal Cord Motor Neurons by Intra-Uterine Delivery of Integration-Deficient Lentiviral Vectors.
Karda, R., Perocheau, D.P., Suff, N., Ng, J., Delhove, J.M.K.M., Buckley, S.M.K., ...Johnson, M.R. (2017). Continual conscious bioluminescent imaging in freely moving somatotransgenic mice.. Sci Rep, 7 (1), 6374. doi:10.1038/s41598-017-06696-w
Karda, R., Perocheau, D.P., Suff, N., Ng, J., Delhove, J.M.K.M., Buckley, S.M.K., ...Johnson, M.R. (2017). Continual conscious bioluminescent imaging in freely moving somatotransgenic mice.. Sci Rep, 7 (1), 6374. doi:10.1038/s41598-017-06696-w
Karda, R., Karbowniczek, K., Caproni, L., Waddington, S.N., Tite, J. (2017). Creation of lentivirus vectors using novel DNA constructs.
Baruteau, J., Waddington, S.N., Alexander, I.E., Gissen, P. (2017). Delivering efficient liver-directed AAV-mediated gene therapy.. Gene Therapy, doi:10.1038/gt.2016.90
Vink, C.A., Counsell, J.R., Perocheau, D.P., Karda, R., Buckley, S.M.K., Brugman, M.H., ...Waddington, S.N. (2017). Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy.. Molecular Therapy, doi:10.1016/j.ymthe.2017.04.028
Vink, C.A., Counsell, J.R., Perocheau, D.P., Karda, R., Buckley, S.M.K., Brugman, M.H., ...Waddington, S.N. (2017). Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy.. Molecular Therapy, doi:10.1016/j.ymthe.2017.04.028
Alonso-Ferrero, M.E., van Til, N.P., Bartolovic, K., Mata, M.F., Wagemaker, G., Moulding, D., ...Milsom, M.D. (2017). Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors. Experimental hematology, doi:10.1016/j.exphem.2017.09.003
Baruteau, J., Jameson, E., Morris, A.A., Chakrapani, A., Santra, S., Vijay, S., ...Murphy, E. (2017). Expanding the phenotype in argininosuccinic aciduria: need for new therapies.. J Inherit Metab Dis, doi:10.1007/s10545-017-0022-x
Baruteau, J., Waddington, S.N., Alexander, I.E., Gissen, P. (2017). Gene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects.. Journal of inherited metabolic disease, doi:10.1007/s10545-017-0053-3
Ahmed, S.G., Waddington, S.N., Boza-Morán, M.G., Yáñez-Muñoz, R.J. (2017). High-efficiency transduction of spinal cord motor neurons by intrauterine delivery of integration-deficient lentiviral vectors.. Journal of controlled release : official journal of the Controlled Release Society, doi:10.1016/j.jconrel.2017.12.029
Mattar, C.N.Z., Gil-Farina, I., Rosales, C., Johana, N., Tan, Y.Y.W., McIntosh, J., ...Choolani, M. (2017). In Utero Transfer of Adeno-Associated Viral Vectors Produces Long-Term Factor IX Levels in a Cynomolgus Macaque Model. Molecular Therapy, doi:10.1016/j.ymthe.2017.04.003
Massaro, G., Perocheau, D., Cuka, S., Hughes, M.P., Baker, R., Karlsson, S., ...Rahim, A.A. (2017). Intravenously administered gene therapy for the treatment of neuronopathic Gaucher Disease.
Counsell, J.R., Asgarian, Z., Meng, J., Ferrer, V., Vink, C.A., Howe, S.J., ...Morgan, J.E. (2017). Lentiviral vectors can be used for full-length dystrophin gene therapy. SCIENTIFIC REPORTS, 7 doi:10.1038/srep44775
Counsell, J.R., Asgarian, Z., Meng, J., Ferrer, V., Vink, C.A., Howe, S.J., ...Morgan, J.E. (2017). Lentiviral vectors can be used for full-length dystrophin gene therapy (vol 7, 44775, 2017). SCIENTIFIC REPORTS, 7 doi:10.1038/srep46880
Counsell, J.R., Asgarian, Z., Meng, J., Ferrer, V., Vink, C.A., Howe, S.J., ...Morgan, J.E. (2017). Lentiviral vectors can be used for full-length dystrophin gene therapy.. Sci Rep, 7 (1), 79. doi:10.1038/s41598-017-00152-5
Delhove, J.M., Buckley, S.M., Perocheau, D.P., Karda, R., Arbuthnot, P., Henderson, N.C., ...McKay, T.R. (2017). Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice.. Scientific Reports, 7 41874. doi:10.1038/srep41874
Delhove, J.M., Buckley, S.M., Perocheau, D.P., Karda, R., Arbuthnot, P., Henderson, N.C., ...McKay, T.R. (2017). Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice.. Scientific Reports, 7 41874. doi:10.1038/srep41874
Counsell, J.R., Vink, C.A., Karda, R., Perocheau, D.P., Brugman, M.H., Buckley, S.M., ...Howe, S.J. (2017). LTR1 Vectors Enhance Safety in Gene Therapy and Can Be Exploited for Rapid, Transient Gene Delivery.
Counsell, J.R., Vink, C.A., Karda, R., Perocheau, D.P., Brugman, M.H., Buckley, S.M., ...Howe, S.J. (2017). LTR1 Vectors Enhance Safety in Gene Therapy and Can Be Exploited for Rapid, Transient Gene Delivery.
Baruteau, J., Perocheau, D.P., Hanley, J., Rocha-Ferreira, E., Karda, R., Ng, J., ...Prunty, H. (2017). Rescue and Phenotypic Correction in Argininosuccinate Lyase-Deficient Mice by AAV8.ASL Transfer.
Baruteau, J., Perocheau, D.P., Hanley, J., Rocha-Ferreira, E., Karda, R., Ng, J., ...Prunty, H. (2017). Rescue and Phenotypic Correction in Argininosuccinate Lyase-Deficient Mice by AAV8.ASL Transfer.
Suff, N., Waddington, S.N. (2017). The power of bioluminescence imaging in understanding host-pathogen interactions.. Methods (San Diego, Calif.), doi:10.1016/j.ymeth.2017.07.001
Hanley, J., Kumar Dhar, D., Mazzacuva, F., Fiadeiro, R., Burden, J.J., Lyne, A.M., ...Virasami, A. (2017). Vps33b is Crucial for Structural and Functional Hepatocyte Polarity.. Journal of Hepatology, doi:10.1016/j.jhep.2017.01.001

2016

Waddington, S.N., Privolizzi, R., Karda, R., O'Neill, H.C. (2016). A Broad Overview and Review of CRISPR-Cas Technology and Stem Cells.. Current stem cell reports, 2 9-20. doi:10.1007/s40778-016-0037-5
Suff, N., Karda, R., Perocheau, D., Delhove, J.M., McKay, T.R., Tangney, M., ...Waddington, S.N. (2016). A Light-Producing Model of Infection-Related Preterm Birth.
Suff, N., Karda, R., Perocheau, D., Delhove, J.M., McKay, T.R., Tangney, M., ...Waddington, S.N. (2016). A Light-Producing Model of Infection-Related Preterm Birth.
Baruteau, J., Hanley, J., Buckley, S.M., Gissen, P., Howe, S.J., Karda, R., ...Suff, N. (2016). AAV8-mediated gene therapy rescue of lethal Argininosuccinate lyase-deficient mice..
Baruteau, J., Hanley, J., Buckley, S.M., Gissen, P., Howe, S.J., Karda, R., ...Suff, N. (2016). AAV8-mediated gene therapy rescue of lethal Argininosuccinate lyase-deficient mice..
Karda, R., Buckley, S.M.K., Waddington, S.N. (2016). Gene Therapy with Adeno-associated Virus for Cystic Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193 (3), 234-236.
Karda, R., Buckley, S.M.K., Waddington, S.N. (2016). Gene Therapy with Adeno-associated Virus for Cystic Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193 (3), 234-236.
Suff, N., Karda, R., Buckley, S.M.K., Delhove, J.M., McKay, T.R., Tangney, M., ...Peebles, D. (2016). Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Infection-Related Preterm Birth..
Suff, N., Karda, R., Buckley, S.M.K., Delhove, J.M., McKay, T.R., Tangney, M., ...Peebles, D. (2016). Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Infection-Related Preterm Birth..
Karda, R., Perocheau, D.P., Suff, N., Ng, J., Hughes, M., Rahim, A.A., ...Henckaerts, E. (2016). Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors.
Karda, R., Perocheau, D.P., Buckley, S.M.K., Delhove, J.M.K.M., Hughes, M., Rahim, A., ...Martin, N.P. (2016). Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors.
Karda, R., Perocheau, D.P., Buckley, S.M.K., Delhove, J.M.K.M., Hughes, M., Rahim, A., ...Martin, N.P. (2016). Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors.
Karda, R., Perocheau, D.P., Suff, N., Ng, J., Hughes, M., Rahim, A.A., ...Henckaerts, E. (2016). Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors.
Karda, R., Perocheau, D.P., Buckley, S.M.K., Delhove, J.M.K.M., Hughes, M., Rahim, A.A., ...Mckay, T.R. (2016). Generation of Light-Producing, Somatic-Transgenic Mice Using Lentivirus and Adeno-Associated Virus Vectors.
Karda, R., Perocheau, D.P., Buckley, S.M.K., Delhove, J.M.K.M., Hughes, M., Rahim, A.A., ...Mckay, T.R. (2016). Generation of Light-Producing, Somatic-Transgenic Mice Using Lentivirus and Adeno-Associated Virus Vectors.
Kao, V.Y.-.C., Ferreira, S., Waddington, S.N., Antoniou, M.N. (2016). Haemophilia B Curative FIX Production from a Low Dose UCOE-based Lentiviral Vector Following Hepatic Pre-natal Delivery. CURRENT GENE THERAPY, 16 (4), 231-241. doi:10.2174/1566523216666161102150101
Migale, R., MacIntyre, D.A., Cacciatore, S., Lee, Y.S., Hagberg, H., Herbert, B.R., ...Bennett, P.R. (2016). Modeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomics. BMC MEDICINE, 14 doi:10.1186/s12916-016-0632-4
Ng, J., Zhen, J., Meyer, E., Erreger, K., Pope, S., Borck, G., ...Waddington, S.N. (2016). Novel therapeutic approaches for childhood parkinsonism.
Hawkins, K.E., Joy, S., Delhove, J.M.K.M., Kotiadis, V.N., Fernandez, E., Fitzpatrick, L.M., ...Duchen, M.R. (2016). NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming. CELL REPORTS, 14 (8), 1883-1891. doi:10.1016/j.celrep.2016.02.003
Buckinx, R., Van Remoortel, S., Gijsbers, R., Waddington, S.N., Timmermans, J.-.P. (2016). Proof-of-concept: neonatal intravenous injection of adeno-associated virus vectors results in successful transduction of myenteric and submucosal neurons in the mouse small and large intestine. NEUROGASTROENTEROLOGY AND MOTILITY, 28 (2), 299-305. doi:10.1111/nmo.12724
Banushi, B., Forneris, F., Straatman-Iwanowska, A., Strange, A., Lyne, A.M., Rogerson, C., ...Doykov, I. (2016). Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis. Nature Communications, 7 doi:10.1038/ncomms12111
Migale, R., MacIntyre, D.A., Cacciatore, S., Lee, Y.S., Herbert, B.R., Waddington, S.N., ...Bennett, P.R. (2016). Relative Contribution of Hormonal and Inflammatory Pathways to Uterine Transcriptome Dynamics in Term and Preterm Labor.
Edey, L.F., O'Dea, K.P., Herbert, B.R., Hua, R., Waddington, S.N., MacIntyre, D.A., ...Johnson, M.R. (2016). The Local and Systemic Immune Response to Intrauterine LPS in the Prepartum Mouse.. Biol Reprod, 95 (6), 125. doi:10.1095/biolreprod.116.143289
Karda, R., Counsell, J.R., Vink, C.A., Perocheau, D.P., Buckley, S.M.K., Ng, J., ...Howe, S.J. (2016). Transduction of the Central Nervous System with the LTR1 Lentiviral Backbone.
Karda, R., Counsell, J.R., Vink, C.A., Perocheau, D.P., Buckley, S.M.K., Ng, J., ...Howe, S.J. (2016). Transduction of the Central Nervous System with the LTR1 Lentiviral Backbone.

2015

Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Perocheau, D.P., Rahim, A.A., Rocha-Ferreira, E., ...Hagberg, H.H. (2015). Conscious whole body bioluminescence in somatic-transgenic rodents can be used to quantify and predict brain damage in a mouse model of Cerebral Palsy.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Perocheau, D.P., Rahim, A.A., Rocha-Ferreira, E., ...Hagberg, H.H. (2015). Conscious whole body bioluminescence in somatic-transgenic rodents can be used to quantify and predict brain damage in a mouse model of Cerebral Palsy.
Shangaris, P., Loukogeorgakis, S., Subramanian, S., Blundell, M., Bakhamis, N., Liu, S., ...Urbani, L. (2015). Correction of Haemoglobin Levels in a Humanized Mouse Model of β-thalassemia after Fetal Gene Therapy.
Ng, J., Karda, R., Massaro, G., Meyer, E., Barrel, S., Baruteau, J., ...Kurian, M.A. (2015). Evaluating Promoter Regulated Dopaminergic Neuron Targeting with AAV9 Delivered To the Neonatal Mouse.
Ng, J., Karda, R., Massaro, G., Meyer, E., Barrel, S., Baruteau, J., ...Kurian, M.A. (2015). Evaluating Promoter Regulated Dopaminergic Neuron Targeting with AAV9 Delivered To the Neonatal Mouse.
Nivsarkar, M.S., Buckley, S.M.K., Parker, A.L., Perocheau, D., Mckay, T.R., Rahim, A.A., ...Waddington, S.N. (2015). Evidence for Contribution of CD4+CD25+Regulatory T Cells in Maintaining Immune Tolerance to Human Factor IX following Perinatal Adenovirus Vector Delivery. JOURNAL OF IMMUNOLOGY RESEARCH, doi:10.1155/2015/397879
Nivsarkar, M.S., Buckley, S.M.K., Parker, A.L., Perocheau, D., Mckay, T.R., Rahim, A.A., ...Waddington, S.N. (2015). Evidence for Contribution of CD4+CD25+Regulatory T Cells in Maintaining Immune Tolerance to Human Factor IX following Perinatal Adenovirus Vector Delivery. JOURNAL OF IMMUNOLOGY RESEARCH, doi:10.1155/2015/397879
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Rahim, A.A., Rocha-Ferreira, E., Perocheau, D., ...Waddington, S.N. (2015). Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Hypoxic Ischaemic Encephalopathy.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Rahim, A.A., Rocha-Ferreira, E., Perocheau, D.P.B., ...Waddington, S.N. (2015). Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Hypoxic Ischaemic Encephalopathy.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Rahim, A.A., Rocha-Ferreira, E., Perocheau, D., ...Waddington, S.N. (2015). Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Hypoxic Ischaemic Encephalopathy.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Rahim, A.A., Rocha-Ferreira, E., Perocheau, D.P.B., ...Waddington, S.N. (2015). Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Hypoxic Ischaemic Encephalopathy.
Buckley, S.M.K., Delhove, J.M.K.M., Perocheau, D.P., Karda, R., Rahim, A.A., Howe, S.J., ...Arbuthnot, P. (2015). In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters. SCIENTIFIC REPORTS, 5 doi:10.1038/srep11842
Buckley, S.M.K., Delhove, J.M.K.M., Perocheau, D.P., Karda, R., Rahim, A.A., Howe, S.J., ...Arbuthnot, P. (2015). In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters. SCIENTIFIC REPORTS, 5 doi:10.1038/srep11842
Massaro, G., Perocheau, D., Karlsson, S., Cheng, S.H., Waddington, S.N., Rahim, A.A. (2015). Intravenously administered gene therapy for the treatment of neuronopathic Gaucher Disease.
Counsell, J.R., Vink, C.A., Perocheau, D.P.B., Karda, R., Ng, J., Buckley, S.M.K., ...Brugman, M.H. (2015). Novel LTR-1 Lentiviral Vectors Are Fully Functional Following the Removal of HIV-1 Gag-RRE Sequences.
Counsell, J.R., Vink, C.A., Perocheau, D.P.B., Karda, R., Ng, J., Buckley, S.M.K., ...Brugman, M.H. (2015). Novel LTR-1 Lentiviral Vectors Are Fully Functional Following the Removal of HIV-1 Gag-RRE Sequences.
Cuka, S., Ng, J., Seino, K.-.I., Waddington, S.N., Kurian, M.A., Rahim, A.A. (2015). Novel therapeutic strategies in NBIA: A gene therapy approach for PLA2G6-associated.
Delhove, J.M.K.M., Perocheau, D., Buckley, S.M.K., Karda, R., Waddington, S.N., McKay, T.R. (2015). Real-Time Monitoring of Transcription Factor Activity Using In Vitro and In Vivo Models of Cholestasis.
Delhove, J.M.K.M., Perocheau, D., Buckley, S.M.K., Karda, R., Waddington, S.N., McKay, T.R. (2015). Real-Time Monitoring of Transcription Factor Activity Using In Vitro and In Vivo Models of Cholestasis.
Pirianov, G., MacIntyre, D.A., Lee, Y., Waddington, S.N., Terzidou, V., Mehmet, H., Bennett, P.R. (2015). Specific inhibition of c-Jun N-terminal kinase delays preterm labour and reduces mortality. REPRODUCTION, 150 (4), 269-277. doi:10.1530/REP-15-0258
Migale, R., Herbert, B.R., Lee, Y.S., Sykes, L., Waddington, S.N., Peebles, D., ...MacIntyre, D.A. (2015). Specific Lipopolysaccharide Serotypes Induce Differential Maternal and Neonatal Inflammatory Responses in a Murine Model of Preterm Labor. AMERICAN JOURNAL OF PATHOLOGY, 185 (9), 2390-2401. doi:10.1016/j.ajpath.2015.05.015
Mattar, C.N., Wong, A.M.S., Hoefer, K., Alonso-Ferrero, M.E., Buckley, S.M.K., Howe, S.J., ...Rahim, A.A. (2015). Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates. FASEB JOURNAL, 29 (9), 3876-3888. doi:10.1096/fj.14-269092
Mattar, C.N., Wong, A.M.S., Hoefer, K., Alonso-Ferrero, M.E., Buckley, S.M.K., Howe, S.J., ...Rahim, A.A. (2015). Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates. FASEB JOURNAL, 29 (9), 3876-3888. doi:10.1096/fj.14-269092
Perocheau, D.P.B., Buckley, S.M.K., Delhove, J.M.K.M., Karda, R., Mckay, T.R., Waddington, S.N. (2015). Use of Somatotransgenic Bioimaging as a Platform for Studying NFkB Pathway in a Tissue-Specific Manner in Two Mouse Models of Inflammation: Rheumatoid Arthritis and Contact Dermatitis.
Perocheau, D.P.B., Buckley, S.M.K., Delhove, J.M.K.M., Karda, R., Mckay, T.R., Waddington, S.N. (2015). Use of Somatotransgenic Bioimaging as a Platform for Studying NFkB Pathway in a Tissue-Specific Manner in Two Mouse Models of Inflammation: Rheumatoid Arthritis and Contact Dermatitis.

2014

MacIntyre, D.A., Lee, Y.S., Migale, R., Herbert, B.R., Waddington, S.N., Peebles, D., ...Bennett, P.R. (2014). Activator protein 1 is a key terminal mediator of inflammation-induced preterm labor in mice.. FASEB JOURNAL, 28 (5), 2358-2368. doi:10.1096/fj.13-247783
Hughes, M.P., Howe, S.J., Buckley, S.M., Waddington, S.N., Rahim, A.A. (2014). An evaluation of viral vector-mediated gene delivery to the murine neonatal brain.
Hughes, M.P., Howe, S.J., Buckley, S.M., Waddington, S.N., Rahim, A.A. (2014). An evaluation of viral vector-mediated gene delivery to the murine neonatal brain.
Baruteau, J., Hanley, J., Buckley, S.M., Gissen, P., Howe, S.J., Karda, R., ...Rahim, A.A. (2014). Elongation factor 1 alpha as a potential promoter for gene therapy in a murine model of both urea cycle defects and systemic disease: argininosuccinic aciduria.
Baruteau, J., Hanley, J., Buckley, S.M., Gissen, P., Howe, S.J., Karda, R., ...Rahim, A.A. (2014). Elongation factor 1 alpha as a potential promoter for gene therapy in a murine model of both urea cycle defects and systemic disease: argininosuccinic aciduria.
Di Matteo, M., Samara-Kuko, E., Ward, N.J., Waddingon, S.N., McVey, J.H., Chuah, M.K.L., VandenDriessche, T. (2014). Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy. MOLECULAR THERAPY, 22 (9), 1614-1624. doi:10.1038/mt.2014.131
Rahim, A.A., Burke, D.G., Buckley, S.M., Cullen, E., Mukherji, S., Mills, K., ...Hughes, D.A. (2014). Perinatal gene therapy ameliorates a mouse model of neuronopathic Gaucher disease.
Rahim, A.A., Burke, D.G., Buckley, S.M., Cullen, E., Mukherji, S., Mills, K., ...Hughes, D.A. (2014). Perinatal gene therapy ameliorates a mouse model of neuronopathic Gaucher disease.
Karda, R., Buckley, S.M.K., Mattar, C.N., Ng, J., Massaro, G., Hughes, M.P., ...Chan, J.K.Y. (2014). Perinatal systemic gene delivery using adeno-associated viral vectors.. FRONTIERS IN MOLECULAR NEUROSCIENCE, 7 doi:10.3389/fnmol.2014.00089
Karda, R., Buckley, S.M.K., Mattar, C.N., Ng, J., Massaro, G., Hughes, M.P., ...Chan, J.K.Y. (2014). Perinatal systemic gene delivery using adeno-associated viral vectors.. FRONTIERS IN MOLECULAR NEUROSCIENCE, 7 doi:10.3389/fnmol.2014.00089
Fan, Y., Marcy, G., Lee, E.S.M., Rozen, S., Mattar, C.N.Z., Waddington, S.N., ...Chan, J.K.Y. (2014). Regionally-specified second trimester fetal neural stem cells reveals differential neurogenic programming.. PLOS ONE, 9 (9), doi:10.1371/journal.pone.0105985
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Ward, N.J., Rahim, A.A., Herbert, B., ...Johnson, M.R. (2014). Somatic Transgenesis of the Central Nervous System for Disease Modelling and Treatment. REPRODUCTIVE SCIENCES, 21 (3), 276A-277A.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Ward, N.J., Rahim, A.A., Herbert, B., ...Johnson, M.R. (2014). Somatic Transgenesis of the Central Nervous System for Disease Modelling and Treatment. REPRODUCTIVE SCIENCES, 21 (3), 276A-277A.
Buckley, S.M., Delhove, J.M., Karda, R., Perocheau, D., Rahim, A.A., Waddington, S.N., McKay, T.R. (2014). Somatotransgenic Bioimaging: Modelling Disease Progression or Therapeutic Amelioration By Continued Tissue-Specific Bioluminescence Imaging in Living Small Animals.
Buckley, S.M., Delhove, J.M., Karda, R., Perocheau, D., Rahim, A.A., Waddington, S.N., McKay, T.R. (2014). Somatotransgenic Bioimaging: Modelling Disease Progression or Therapeutic Amelioration By Continued Tissue-Specific Bioluminescence Imaging in Living Small Animals.
Jonuschies, J., Antoniou, M., Waddington, S., Boldrin, L., Muntoni, F., Thrasher, A., Morgan, J. (2014). The Human Desmin Promoter Drives Robust Gene Expression for Skeletal Muscle Stem Cell-Mediated Gene Therapy. CURRENT GENE THERAPY, 14 (4), 276-288. doi:10.2174/1566523214666140612154521
Migale, R., MacIntyre, D.A., Lee, Y.S., Charalambous, A., Herbert, B.R., Waddington, S.N., ...Bennett, P.R. (2014). TLR4-Mediated Activation of AP-1 Drives the Expression of Labour Associated Genes in Mouse Myometrium. REPRODUCTIVE SCIENCES, 21 (3), 249A.
Migale, R., MacIntyre, D.A., Lee, Y.S., Charalambous, A., Herbert, B.R., Waddington, S.N., ...Bennett, P.R. (2014). TLR4-mediated activation of AP-1 drives the expression of labour associated genes in mouse myometrium. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 121 (7), E10.
Condiotti, R., Goldenberg, D., Giladi, H., Schnitzer-Perlman, T., Waddington, S.N., Buckley, S.M., ...Coutelle, C. (2014). Transduction of fetal mice with a feline lentiviral vector induces liver tumors which exhibit an E2F activation signature.. MOLECULAR THERAPY, 22 (1), 59-68. doi:10.1038/mt.2013.193
Condiotti, R., Goldenberg, D., Giladi, H., Schnitzer-Perlman, T., Waddington, S.N., Buckley, S.M., ...Coutelle, C. (2014). Transduction of fetal mice with a feline lentiviral vector induces liver tumors which exhibit an E2F activation signature.. MOLECULAR THERAPY, 22 (1), 59-68. doi:10.1038/mt.2013.193
Alonso-Ferrero, M.E., Bartolovic, K., Kinnon, C., Mata, M., Waddington, S.N., Milsom, M.D., ...Howe, S.J. (2014). Transient Expression of Genes From Integrative Deficient Lentiviral Vectors Improves Blood Progenitor Cell Expansion, Survival and Engraftment.

2013

Mattar, C.N., Rosales, C., Fragata, R., McIntosh, J., Johana, N., Waddington, S.N., ...Biswas, A. (2013). A robust preclinical model for fetal gene therapy: strategies targeting the liver for molecular correction of congenital single gene defects at early and late gestation. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 120 5.
Batten, C.A., Henstock, M.R., Steedman, H.M., Waddington, S., Edwards, L., Oura, C.A.L. (2013). Bluetongue virus serotype 26: Infection kinetics, pathogenesis and possible contact transmission in goats. VETERINARY MICROBIOLOGY, 162 (1), 62-67. doi:10.1016/j.vetmic.2012.08.014
Burke, D.G., Rahim, A.A., Waddington, S.N., Karlsson, S., Enquist, I., Bhatia, K., ...Heales, S. (2013). Erratum to: Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes.. JOURNAL OF INHERITED METABOLIC DISEASE, 36 (6), 1089. doi:10.1007/s10545-013-9599-x
Disterer, P., Al-Shawi, R., Ellmerich, S., Waddington, S.N., Owen, J.S., Simons, J.P., Khoo, B. (2013). Exon Skipping of Hepatic APOB pre-mRNA with Splice-switching Oligonucleotides Reduces LDL Cholesterol In Vivo. Molecular Therapy, doi:10.1038/mt.2012.264
Rahim, A.A., Sirka, E., Burke, D.G., Buckley, S.M., Cullen, E., Mukherji, S., ...Hughes, D.A. (2013). In utero gene therapy rescue of an acute neonatal lethal mouse model of neuropathic Gaucher Disease.
Rahim, A.A., Sirka, E., Burke, D.G., Buckley, S.M., Cullen, E., Mukherji, S., ...Hughes, D.A. (2013). In utero gene therapy rescue of an acute neonatal lethal mouse model of neuropathic Gaucher Disease.
Burke, D.G., Rahim, A.A., Waddington, S.N., Karlsson, S., Enquist, I., Bhatia, K., ...Heales, S. (2013). Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes.. JOURNAL OF INHERITED METABOLIC DISEASE, 36 (5), 869-872. doi:10.1007/s10545-012-9561-3
Aitchison, K.L., Rahim, A.A., Reed, M., Burke, D.G., Hughes, D.A., Heales, S., ...Howe, S.J. (2013). Lentiviral vectors for gene therapy of type I Gaucher disease.
Osellame, L.D., Rahim, A.A., Hargreaves, I.P., Gegg, M.E., Richard-Londt, A., Brandner, S., ...Duchen, M.R. (2013). Mitochondria and quality control defects in a mouse model of Gaucher disease - links to Parkinson’s Disease. Cell Metabolism, 17 (6), 941-53.-953.. doi:10.1016/j.cmet.2013.04.014
Parker, A.L., White, K.M., Lavery, C.A., Custers, J., Waddington, S.N., Baker, A.H. (2013). Pseudotyping the adenovirus serotype 5 capsid with both the fibre and penton of serotype 35 enhances vascular smooth muscle cell transduction. GENE THERAPY, 20 (12), 1158-1164. doi:10.1038/gt.2013.44
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Ward, N.J., Rahim, A.A., Herbert, B., ...Johnson, M.R. (2013). Somatic transgenesis of the central nervous system for disease modelling and treatment.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Ward, N.J., Rahim, A.A., Herbert, B., ...Johnson, M.R. (2013). Somatic transgenesis of the central nervous system for disease modelling and treatment.
Buckley, S.M.K., Delhove, J., Karda, R., Waddington, S.N., McKay, T.R. (2013). Somatotransgenic bioimaging: a novel biosensing platform for in vivo bioimaging.
Buckley, S.M.K., Delhove, J., Karda, R., Waddington, S.N., McKay, T.R. (2013). Somatotransgenic bioimaging: a novel biosensing platform for in vivo bioimaging.
Mattar, C.N., Waddington, S.N., Biswas, A., Johana, N., Ng, X.W., Fisk, A.S., ...Buckley, S.M.K. (2013). Systemic delivery of scAAV9 in fetal macaques facilitates neuronal transduction of the central and peripheral nervous systems.. GENE THERAPY, 20 (1), 69-83. doi:10.1038/gt.2011.216
Mattar, C.N., Waddington, S.N., Biswas, A., Johana, N., Ng, X.W., Fisk, A.S., ...Buckley, S.M.K. (2013). Systemic delivery of scAAV9 in fetal macaques facilitates neuronal transduction of the central and peripheral nervous systems.. GENE THERAPY, 20 (1), 69-83. doi:10.1038/gt.2011.216
Nowrouzi, A., Cheung, W.T., Li, T., Zhang, X., Arens, A., Paruzynski, A., ...von Kalle, C. (2013). The fetal mouse is a sensitive genotoxicity model that exposes lentiviral-associated mutagenesis resulting in liver oncogenesis.. MOLECULAR THERAPY, 21 (2), 324-337. doi:10.1038/mt.2012.224
Nowrouzi, A., Cheung, W.T., Li, T., Zhang, X., Arens, A., Paruzynski, A., ...von Kalle, C. (2013). The fetal mouse is a sensitive genotoxicity model that exposes lentiviral-associated mutagenesis resulting in liver oncogenesis.. MOLECULAR THERAPY, 21 (2), 324-337. doi:10.1038/mt.2012.224
McIntosh, J., Lenting, P.J., Rosales, C., Lee, D., Rabbanian, S., Raj, D., ...McVey, J.H. (2013). Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant. BLOOD, 121 (17), 3335-3344. doi:10.1182/blood-2012-10-462200
Ridley, C.M., Thur, K.E., Shanahan, J., Thillaiappan, N.B., Shen, A., Uhl, K., ...Platt, F.M. (2013). β-Glucosidase 2 (GBA2) activity and imino sugar pharmacology.. JOURNAL OF BIOLOGICAL CHEMISTRY, 288 (36), 26052-26066. doi:10.1074/jbc.M113.463562

2012

Herbert, B.R., Hua, R., Waddington, S.N., Sooranna, S.R., Johnson, M.R. (2012). Absence of Maternal CCR2 Reduces the Adverse Effects of LPS-Induced Inflammation on Neonatal Outcome. REPRODUCTIVE SCIENCES, 19 (S3), 120A.
Roybal, J.L., Endo, M., Buckley, S.M.K., Herbert, B.R., Waddington, S.N., Flake, A.W. (2012). Animal models for prenatal gene therapy: Rodent models for prenatal gene therapy. Methods in Molecular Biology, 891 201-218. doi:10.1007/978-1-61779-873-3_10
Roybal, J.L., Endo, M., Buckley, S.M.K., Herbert, B.R., Waddington, S.N., Flake, A.W. (2012). Animal models for prenatal gene therapy: rodent models for prenatal gene therapy.. Methods in molecular biology (Clifton, N.J.), 891 201-218.
Roybal, J.L., Endo, M., Buckley, S.M.K., Herbert, B.R., Waddington, S.N., Flake, A.W. (2012). Animal models for prenatal gene therapy: rodent models for prenatal gene therapy.. Methods in Molecular Biology, 891 201-218. doi:10.1007/978-1-61779-873-3_10
Roybal, J.L., Endo, M., Buckley, S.M.K., Herbert, B.R., Waddington, S.N., Flake, A.W. (2012). Animal models for prenatal gene therapy: rodent models for prenatal gene therapy.. Methods in molecular biology (Clifton, N.J.), 891 201-218.
David, A.L., Waddington, S.N. (2012). Candidate diseases for prenatal gene therapy.. In (pp. 9-39). .
David, A.L., Waddington, S.N. (2012). Candidate diseases for prenatal gene therapy.. Methods in molecular biology (Clifton, N.J.), 891 9-39.
Coughlan, L., Waddington, S.N., Buckley, S.M., Campton, J., Custers, J., Nicklin, S.A., Baker, A.H. (2012). CD46 Does Not Affect the In Vivo Biodistribution of Species D Adenoviruses, Ad26 or Ad48 in CD46 Transgenic Mice Following IV Delivery.
Coughlan, L., Waddington, S.N., Buckley, S.M., Campton, J., Custers, J., Nicklin, S.A., Baker, A.H. (2012). CD46 Does Not Affect the In Vivo Biodistribution of Species D Adenoviruses, Ad26 or Ad48 in CD46 Transgenic Mice Following IV Delivery.
Delhove, J.M.K.M., Rahim, A.A., McKay, T.R., Waddington, S.N., Buckley, S.M.K. (2012). Choice of surrogate and physiological markers for prenatal gene therapy.. Methods in Molecular Biology, 891 273-290. doi:10.1007/978-1-61779-873-3_13
Delhove, J.M.K.M., Rahim, A.A., McKay, T.R., Waddington, S.N., Buckley, S.M.K. (2012). Choice of surrogate and physiological markers for prenatal gene therapy.. Methods in molecular biology (Clifton, N.J.), 891 273-290.
Delhove, J.M.K.M., Rahim, A.A., McKay, T.R., Waddington, S.N., Buckley, S.M.K. (2012). Choice of surrogate and physiological markers for prenatal gene therapy.. Methods in Molecular Biology, 891 273-290. doi:10.1007/978-1-61779-873-3_13
Delhove, J.M.K.M., Rahim, A.A., McKay, T.R., Waddington, S.N., Buckley, S.M.K. (2012). Choice of surrogate and physiological markers for prenatal gene therapy.. Methods in molecular biology (Clifton, N.J.), 891 273-290.
Aitchison, K.L., Rahim, A.A., Hughes, D., Kinnon, C., Waddington, S.N., Howe, S.J. (2012). Developing lentiviral vectors for gene therapy of Type I Gaucher Disease.
Delhove, J.M.K.M., Waddington, S.N., Ward, N.J., Jathoul, A.P., Pule, M.A., McKay, T.R., Buckley, S.M.K. (2012). Development of bicistronic lentiviral vectors for continual in vivo and endpoint analysis of gene and stem cell transfer.
Delhove, J.M.K.M., Waddington, S.N., Ward, N.J., Jathoul, A.P., Pule, M.A., McKay, T.R., Buckley, S.M.K. (2012). Development of bicistronic lentiviral vectors for continual in vivo and endpoint analysis of gene and stem cell transfer.
Le Friec, G., Sheppard, D., Karsten, C.M., Whiteman, P., Shamoun, S., Laing, A., ...Couzi, L. (2012). Identification of Jagged1 as a novel ligand for CD46: An interaction required for normal induction and regulation of human TH1 responses. IMMUNOBIOLOGY, 217 (11), 1176. doi:10.1016/j.imbio.2012.08.137
Rahim, A.A., Wong, A.M., Hofer, K., Buckley, S.M., Mukherji, S., Cooper, J.D., Waddington, S.N. (2012). Intravenous administration of AAV2/9 to fetal and neonatal mice leads to extensive transduction of visceral organs and intestinal epithelia.
Rahim, A.A., Wong, A.M., Hofer, K., Buckley, S.M., Mukherji, S., Cooper, J.D., Waddington, S.N. (2012). Intravenous administration of AAV2/9 to fetal and neonatal mice leads to extensive transduction of visceral organs and intestinal epithelia.
Coutelle, C., Waddington, S.N., Themis, M. (2012). Monitoring for potential adverse effects of prenatal gene therapy: mouse models for developmental aberrations and inadvertent germ line transmission.. Methods in Molecular Biology, 891 329-340. doi:10.1007/978-1-61779-873-3_15
Coutelle, C., Waddington, S.N., Themis, M. (2012). Monitoring for potential adverse effects of prenatal gene therapy: mouse models for developmental aberrations and inadvertent germ line transmission.. Methods in molecular biology (Clifton, N.J.), 891 329-340.
Mehta, V., Abi-Nader, K.N., Carr, D., Wallace, J., Coutelle, C., Waddington, S.N., ...David, A.L. (2012). Monitoring for potential adverse effects of prenatal gene therapy: use of large animal models with relevance to human application.. In (pp. 291-328). .
Mehta, V., Abi-Nader, K.N., Carr, D., Wallace, J., Coutelle, C., Waddington, S.N., ...David, A.L. (2012). Monitoring for potential adverse effects of prenatal gene therapy: use of large animal models with relevance to human application.. Methods in molecular biology (Clifton, N.J.), 891 291-328.
Ward, N.J., Buckley, S.M.K., Rahim, A.A., McVey, J.H., Waddington, S.N. (2012). Optimised Factor VIII Vectors for Gene Therapy of Haemophilia A.
Ward, N.J., Buckley, S.M.K., Rahim, A.A., McVey, J.H., Waddington, S.N. (2012). Optimised Factor VIII Vectors for Gene Therapy of Haemophilia A.
Rahim, A.A., Wong, A.M., Hoefer, K., Buckley, S.M., Mattar, C.N., Chan, J.K., ...Waddington, S.N. (2012). Systemic Gene Expression after Intravenous Injection of Adeno-Associated Virus 2/9 to Fetal and Neonatal Mice.
Rahim, A.A., Wong, A.M., Hoefer, K., Buckley, S.M., Mattar, C.N., Chan, J.K., ...Waddington, S.N. (2012). Systemic Gene Expression after Intravenous Injection of Adeno-Associated Virus 2/9 to Fetal and Neonatal Mice.
Mattar, C.N., Waddington, S.N., Biswas, A., Davidoff, A.M., Choolani, M., Chan, J.K.Y., Nathwani, A.C. (2012). The case for intrauterine gene therapy. BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY, 26 (5), 697-709. doi:10.1016/j.bpobgyn.2012.06.006
Le Friec, G., Sheppard, D., Whiteman, P., Karsten, C.M., Shamoun, S.A.-.T., Laing, A., ...Chillakuri, C. (2012). The CD46-Jagged1 interaction is critical for human T(H)1 immunity. NATURE IMMUNOLOGY, 13 (12), 1213-+. doi:10.1038/ni.2454
Coutelle, C., Waddington, S.N. (2012). The concept of prenatal gene therapy.. Methods in molecular biology (Clifton, N.J.), 891 1-7.
Coutelle, C., Waddington, S.N. (2012). The concept of prenatal gene therapy.. Methods in Molecular Biology, 891 1-7. doi:10.1007/978-1-61779-873-3_1
Sheppard, D., Whiteman, P., Le Friec, G., Waddington, S.N., Smith, R., Melchionna, T., ...Lea, S.M. (2012). The novel Jagged1/CD46 interaction: A prime target for immune modulation by viruses?. IMMUNOBIOLOGY, 217 (11), 1210-1211. doi:10.1016/j.imbio.2012.08.234
Coutelle, C., Waddington, S.N. (2012). Vector systems for prenatal gene therapy: choosing vectors for different applications.. Methods in Molecular Biology, 891 41-53. doi:10.1007/978-1-61779-873-3_3
Coutelle, C., Waddington, S.N. (2012). Vector systems for prenatal gene therapy: choosing vectors for different applications.. Methods in molecular biology (Clifton, N.J.), 891 41-53.

2011

Binny, C., McIntosh, J., Peruta, M., Kymalainen, H., Tuddenham, E., Waddington, S., ...Thrasher, A. (2011). AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous haemorrhage. HUMAN GENE THERAPY, 22 (10), A45.
Binny, C., McIntosh, J., Peruta, M., Kymalainen, H., Tuddenham, E., Waddington, S., ...Thrasher, A. (2011). AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous haemorrhage. HUMAN GENE THERAPY, 22 (10), A45.
Nathwani, A., Binny, C.J., McIntosh, J.H., Tuddenham, E.G.D., Peruta, M.D., Kymalainen, H., ...Spence, Y. (2011). AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous haemorrhage.. Blood,
Nathwani, A., Binny, C.J., McIntosh, J.H., Tuddenham, E.G.D., Peruta, M.D., Kymalainen, H., ...Spence, Y. (2011). AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous haemorrhage.. Blood,
Ward, N.J., Buckley, S.M.K., Waddington, S.N., Vandendriessche, T., Chuah, M.K.L., Nathwani, A.C., ...Thrasher, A.J. (2011). Codon optimization of human factor VIII cDNAs leads to high-level expression.. BLOOD, 117 (3), 798-807. doi:10.1182/blood-2010-05-282707
Ward, N.J., Buckley, S.M.K., Waddington, S.N., Vandendriessche, T., Chuah, M.K.L., Nathwani, A.C., ...Thrasher, A.J. (2011). Codon optimization of human factor VIII cDNAs leads to high-level expression.. BLOOD, 117 (3), 798-807. doi:10.1182/blood-2010-05-282707
Kao, V.Y.C., Waddington, S.N., Equihua, C.M., Thrasher, A.J., Antoniou, M.N. (2011). Curative F.IX production from low-dose UCOE-lentiviral vectors. HUMAN GENE THERAPY, 22 (10), A110.
Argyros, O., Wong, S.P., Fedonidis, C., Tolmachov, O., Waddington, S.N., Howe, S.J., ...Harbottle, R.P. (2011). Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver. JOURNAL OF MOLECULAR MEDICINE-JMM, 89 (5), 515-529. doi:10.1007/s00109-010-0713-3
Waddington, S.N. (2011). Fetal and neonatal gene therapy. HUMAN GENE THERAPY, 22 (10), A13.
Mattar, C.N., Choolani, M., Biswas, A., Waddington, S.N., Chan, J.K.Y. (2011). Fetal gene therapy: recent advances and current challenges. EXPERT OPINION ON BIOLOGICAL THERAPY, 11 (10), 1257-1271. doi:10.1517/14712598.2011.585153
Rahim, A.A., Wong, A.M., Ahmadi, S., Hoefer, K., Buckley, S.M., Hughes, D.A., ...Cooper, J.D. (2011). In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression. Gene Ther., doi:10.1038/gt.2011.157
Rahim, A.A., Wong, A.M., Ahmadi, S., Hoefer, K., Buckley, S.M.K., Hughes, D.A., ...Cooper, J.D. (2011). In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression.. Gene Ther., doi:10.1038/gt.2011.157
Rahim, A.A., Wong, A.M.S., Hoefer, K., Buckley, S.M.K., Mattar, C.N., Cheng, S.H., ...Waddington, S.N. (2011). Intravenous administration of AAV2/9 to the fetal and neonatal mouse leads to differential targeting of CNS cell types and extensive transduction of the nervous system.. FASEB JOURNAL, 25 (10), 3505-3518. doi:10.1096/fj.11-182311
Rahim, A.A., Wong, A.M.S., Hoefer, K., Buckley, S.M.K., Mattar, C.N., Cheng, S.H., ...Waddington, S.N. (2011). Intravenous administration of AAV2/9 to the fetal and neonatal mouse leads to differential targeting of CNS cell types and extensive transduction of the nervous system.. FASEB JOURNAL, 25 (10), 3505-3518. doi:10.1096/fj.11-182311
Aitchison, K.L., Rahim, A.A., Hughes, D.A., Kinnon, C., Waddington, S.N., Howe, S.J. (2011). Lentiviral vectors for gene therapy of Type I Gaucher Disease. HUMAN GENE THERAPY, 22 (10), A44.
Nathwani, A.C., Rosales, C., McIntosh, J., Rastegarlari, G., Nathwani, D., Raj, D., ...Jackson, S. (2011). Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins.. Mol.Ther., 19 (5), 876-885. doi:10.1038/mt.2010.274
Ward, N.J., Buckley, S.M.K., Rahim, A.A., McVey, J.H., Thrasher, A.J., Waddington, S.N. (2011). Optimised vectors for the treatment of haemophilia A. HUMAN GENE THERAPY, 22 (10), A109.
Ward, N.J., Buckley, S.M.K., Rahim, A.A., McVey, J.H., Thrasher, A.J., Waddington, S.N. (2011). Optimised vectors for the treatment of haemophilia A. HUMAN GENE THERAPY, 22 (10), A109.
Mehta, V., Abi Nader, K., Waddington, S., David, A.L. (2011). Organ targeted prenatal gene therapy--how far are we?. PRENATAL DIAGNOSIS, 31 (7), 720-734. doi:10.1002/pd.2787
Rahim, A.A., Buckley, S.M.K., Chan, J.K.Y., Peebles, D.M., Waddington, S.N. (2011). Perinatal gene delivery to the CNS. Therapeutic Delivery, 2 (4), 483-491. doi:10.4155/tde.11.16
Rahim, A.A., Buckley, S.M.K., Chan, J.K.Y., Peebles, D.M., Waddington, S.N. (2011). Perinatal gene delivery to the CNS. Therapeutic Delivery, 2 (4), 483-491. doi:10.4155/tde.11.16
McKay, T.R., Rahim, A.A., Buckley, S.M.K., Ward, N.J., Chan, J.K.Y., Howe, S.J., Waddington, S.N. (2011). Perinatal gene transfer to the liver.. CURRENT PHARMACEUTICAL DESIGN, 17 (24), 2528-2541.
McKay, T.R., Rahim, A.A., Buckley, S.M.K., Ward, N.J., Chan, J.K.Y., Howe, S.J., Waddington, S.N. (2011). Perinatal gene transfer to the liver.. CURRENT PHARMACEUTICAL DESIGN, 17 (24), 2528-2541.
Shaw, S.W.S., De Coppi, P., Resca, E., Waddington, S.N., David, A.L. (2011). Prenatal congenic amniotic fluid stem cells have a higher engraftment potential for haematopoiesis than allogenic transplantation.
Buckley, S.M.K., Rahim, A.A., Chan, J.K.Y., David, A.L., Peebles, D.M., Coutelle, C., Waddington, S.N. (2011). Recent advances in fetal gene therapy. Therapeutic Delivery, 2 (4), 461-469. doi:10.4155/tde.11.17
Buckley, S.M.K., Rahim, A.A., Chan, J.K.Y., David, A.L., Peebles, D.M., Coutelle, C., Waddington, S.N. (2011). Recent advances in fetal gene therapy. Therapeutic Delivery, 2 (4), 461-469. doi:10.4155/tde.11.17
David, A.L., McIntosh, J., Peebles, D.M., Cook, T., Waddington, S., Weisz, B., ...Davidoff, A.M. (2011). Recombinant Adeno-Associated Virus-Mediated In Utero Gene Transfer Gives Therapeutic Transgene Expression in the Sheep. HUMAN GENE THERAPY, 22 (4), 419-426. doi:10.1089/hum.2010.007
Mattar, C.N., Nathwani, A.C., Waddington, S.N., Dighe, N., Kaeppel, C., Nowrouzi, A., ...Fisk, N.M. (2011). Stable Human FIX Expression After 0.9G Intrauterine Gene Transfer of Self-complementary Adeno-associated Viral Vector 5 and 8 in Macaques. Mol.Ther., 19 (11), 1950-1960. doi:10.1038/mt.2011.107
Rahim, A.A., Wong, A.M.S., Hoefer, K., Buckley, S.M.K., Mattar, C.N., Chan, J.K.Y., ...Waddington, S.N. (2011). Systemic gene expression following intravenous administration of AAV2/9 to fetal and neonatal mice and non-human primates. HUMAN GENE THERAPY, 22 (10), A106-A107.
Rahim, A.A., Wong, A.M.S., Hoefer, K., Buckley, S.M.K., Mattar, C.N., Chan, J.K.Y., ...Waddington, S.N. (2011). Systemic gene expression following intravenous administration of AAV2/9 to fetal and neonatal mice and non-human primates. HUMAN GENE THERAPY, 22 (10), A106-A107.

2010

Hristova, M., Cuthill, D., Zbarsky, V., Acosta-Saltos, A., Wallace, A., Blight, K., ...Waddington, S.N. (2010). Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development. GLIA, 58 (1), 11-28. doi:10.1002/glia.20896
Hristova, M., Cuthill, D., Zbarsky, V., Acosta-Saltos, A., Wallace, A., Blight, K., ...Waddington, S.N. (2010). Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development.. Glia, 58 (1), 11-28.
Hristova, M., Cuthill, D., Zbarsky, V., Acosta-Saltos, A., Wallace, A., Blight, K., ...Waddington, S.N. (2010). Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development.. Glia, 58 (1), 11-28.
Buckley, S.M.K. (2010). An investigation into prenatal gene therapy for cystic fibrosis using intra-amniotic vector application to mouse models..
Alba, R., Bradshaw, A.C., Coughlan, L., Denby, L., McDonald, R.A., Waddington, S.N., ...Miller, A.M. (2010). Biodistribution and retargeting of FX-binding ablated Ad5 vectors. In Press
Alba, R., Bradshaw, A.C., Coughlan, L., Denby, L., McDonald, R.A., Waddington, S.N., ...Miller, A.M. (2010). Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors. BLOOD, 116 (15), 2656-2664. doi:10.1182/blood-2009-12-260026
Alba, R., Bradshaw, A.C., Coughlan, L., Denby, L., McDonald, R.A., Waddington, S.N., ...Miller, A.M. (2010). Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors. BLOOD, 116 (15), 2656-2664. doi:10.1182/blood-2009-12-260026
Shaw, S.W.S., David, A.L., Antoniou, M., Meola, M., Ward, N., De Coppi, P., Waddington, S.N. (2010). Congenic Fetal Delivered Lentivirus UCOE-Luciferase Transduced Amniotic Fluid Stem Cells Preferentially Engraft in the Liver.
Ward, N.J., Buckley, S.M., Waddington, S.N., Nathwani, A.C., Tuddenham, E.G., Kinnon, C., ...McVey, J.H. (2010). Correction of Murine Hemophilia A Using SIN Lentiviral Vectors Expressing Enhanced Human Factor VIII cDNAs.
Ward, N.J., Buckley, S.M., Waddington, S.N., Nathwani, A.C., Tuddenham, E.G., Kinnon, C., ...McVey, J.H. (2010). Correction of Murine Hemophilia A Using SIN Lentiviral Vectors Expressing Enhanced Human Factor VIII cDNAs.
Wong, A.M.S., Rahim, A.A., Waddington, S.N., Cooper, J.D. (2010). Current therapies for the soluble lysosomal forms of neuronal ceroid lipofuscinosis.. BIOCHEMICAL SOCIETY TRANSACTIONS, 38 1484-1488. doi:10.1042/BST0381484
Talbot, G.E., Waddington, S.N., Bales, O., Tchen, R.C., Antoniou, M.N. (2010). Desmin-regulated Lentiviral Vectors for Skeletal Muscle Gene Transfer. MOLECULAR THERAPY, 18 (3), 601-608. doi:10.1038/mt.2009.267
Rahim, A.A., Wong, A.M., Hoeffer, K., Buckley, S.M., Mattar, C., Chan, J., ...Waddington, S.N. (2010). Efficient CNS, PNS, and Visceral Gene Delivery Following Fetal and Neonatal Intravenous Administration of AAV9.
Rahim, A.A., Wong, A.M., Hoeffer, K., Buckley, S.M., Mattar, C., Chan, J., ...Waddington, S.N. (2010). Efficient CNS, PNS, and Visceral Gene Delivery Following Fetal and Neonatal Intravenous Administration of AAV9.
Herbert, B.R., Sykes, L., Waddington, S.N., Johnson, M.R., Bennett, P.R. (2010). From Lights, Camera, Action!... to No Lights, Camera, and Preterm Labour!.
Othman, M., Chirinian, Y., Brown, C., Notley, C., Hickson, N., Hampshire, D., ...Baker, A. (2010). Functional characterization of a 13 bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease. In Press
Othman, M., Chirinian, Y., Brown, C., Notley, C., Hickson, N., Hampshire, D., ...Baker, A. (2010). Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease. BLOOD, 116 (18), 3645-3652. doi:10.1182/blood-2009-12-261131
Othman, M., Chirinian, Y., Brown, C., Notley, C., Hickson, N., Hampshire, D., ...Baker, A. (2010). Functional characterization of a 13-bp deletion (c.-1522--1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease. Blood, 116 (18), 3645-3652. doi:10.1182/blood-2009-12-261131
Waddington, S.N., Crossley, R., Sheard, V., Howe, S.J., Buckley, S.M.K., Coughlan, L., ...McKay, T.R. (2010). Gene delivery of a mutant TGFβ3 reduces markers of scar tissue formation after cutaneous wounding.. MOLECULAR THERAPY, 18 (12), 2104-2111. doi:10.1038/mt.2010.174
Waddington, S.N., Crossley, R., Sheard, V., Howe, S.J., Buckley, S.M.K., Coughlan, L., ...McKay, T.R. (2010). Gene delivery of a mutant TGFβ3 reduces markers of scar tissue formation after cutaneous wounding.. MOLECULAR THERAPY, 18 (12), 2104-2111. doi:10.1038/mt.2010.174
Rahim, A.A., Wong, A.M.S., Buckley, S.M.K., Chan, J.K.Y., David, A.L., Cooper, J.D., ...Waddington, S.N. (2010). In utero gene transfer to the mouse nervous system.. BIOCHEMICAL SOCIETY TRANSACTIONS, 38 1489-1493. doi:10.1042/BST0381489
Rahim, A.A., Wong, A.M.S., Buckley, S.M.K., Chan, J.K.Y., David, A.L., Cooper, J.D., ...Waddington, S.N. (2010). In utero gene transfer to the mouse nervous system.. BIOCHEMICAL SOCIETY TRANSACTIONS, 38 1489-1493. doi:10.1042/BST0381489
Herbert, B., Patel, D., Waddington, S.N., Eden, E.R., McAleenan, A., Sun, X.-.M., Soutar, A.K. (2010). Increased secretion of lipoproteins in transgenic mice expressing human D374Y PCSK9 under physiological genetic control.. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 30 (7), 1333-U151. doi:10.1161/ATVBAHA.110.204040
Al-Allaf, F.A., Coutelle, C., Waddington, S.N., David, A.L., Harbottle, R., Themis, M. (2010). LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress and perspectives.. Int Arch Med, 3 36-.
Grinshpun, A., Condiotti, R., Waddington, S., Peer, M., Zeig, E., Peretz, S., ...Giladi, H. (2010). Neonatal gene therapy of glycogen storage disease type Ia using a feline immunodeficiency virus based vector. In Press
Waddington, S.N., Rahim, A.A., Mattar, C., Wong, A.M.S., Hoeffer, K., Buckley, S.M.K., ...Chan, J. (2010). Perinatal Gene Therapy for Lethal Genetic Diseases.
Waddington, S.N., Rahim, A.A., Mattar, C., Wong, A.M.S., Hoeffer, K., Buckley, S.M.K., ...Chan, J. (2010). Perinatal Gene Therapy for Lethal Genetic Diseases.
Bartolovic, K., Mongkoldhumrongkul, N., Waddington, S.N., Jayasinghe, S.N., Howe, S.J. (2010). The differentiation and engraftment potential of mouse hematopoietic stem cells is maintained after bio-electrospray.. ANALYST, 135 (1), 157-164. doi:10.1039/b917813a

2009

Kennea, N.L., Waddington, S.N., Chan, J., O'Donoghue, K., Yeung, D., Taylor, D.L., ...Edwards, A.D. (2009). Differentiation of human fetal mesenchymal stem cells into cells with an oligodendrocyte phenotype. 8 (7), 1069-1079.
Parker, A.L., Waddington, S.N., Buckley, S.M.K., Custers, J., Havenga, M.J.E., van Rooijen, N., ...Baker, A.H. (2009). Effect of Neutralizing Sera on Factor X-Mediated Adenovirus Serotype 5 Gene Transfer. JOURNAL OF VIROLOGY, 83 (1), 479-483. doi:10.1128/JVI.01878-08
Parker, A.L., Waddington, S.N., Buckley, S.M.K., Custers, J., Havenga, M.J.E., van Rooijen, N., ...Baker, A.H. (2009). Effect of Neutralizing Sera on Factor X-Mediated Adenovirus Serotype 5 Gene Transfer. JOURNAL OF VIROLOGY, 83 (1), 479-483. doi:10.1128/JVI.01878-08
Rahim, A.A., Wong, A.M., Howe, S.J., Buckley, S.M., costa-Saltos, A.D., Elston, K.E., ...Anderson, P.N. (2009). Efficient gene delivery to the adult and fetal CNS using pseudotyped non-integrating lentiviral vectors. Gene Ther., 16 (4), 509-520.
Rahim, A.A., Wong, A.M., Howe, S.J., Buckley, S.M., costa-Saltos, A.D., Elston, K.E., ...Anderson, P.N. (2009). Efficient gene delivery to the adult and fetal CNS using pseudotyped non-integrating lentiviral vectors. Gene Ther., 16 (4), 509-520.
Greig, J.A., Buckley, S.M.K., Waddington, S.N., Parker, A.L., Bhella, D., Pink, R., ...McVey, J.H. (2009). Erratum: "Influence of coagulation factor X on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors" (Molecular Theraphy (2009) 10.1038/mt.2009.152). Molecular Therapy, 17 (10), 1830-. doi:10.1038/mt.2009.186
Greig, J.A., Buckley, S.M.K., Waddington, S.N., Parker, A.L., Bhella, D., Pink, R., ...McVey, J.H. (2009). Erratum: "Influence of coagulation factor X on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors" (Molecular Theraphy (2009) 10.1038/mt.2009.152). Molecular Therapy, 17 (10), 1830-. doi:10.1038/mt.2009.186
Rahim, A.A., Wong, A.M., Buckley, S.M., Hughes, D.A., Karlsson, S., Cooper, J.D., ...Waddington, S.N. (2009). Fetal Gene Therapy for Acute Neuronopathic Gaucher Disease.
Rahim, A.A., Wong, A.M., Buckley, S.M., Hughes, D.A., Karlsson, S., Cooper, J.D., ...Waddington, S.N. (2009). Fetal Gene Therapy for Acute Neuronopathic Gaucher Disease.
Parker, A.L., Waddington, S.N., Miller, A.M., Buckley, S.M., Nicklin, S.A., McClure, J.D., ...Baker, A.H. (2009). Genome Wide and Micro RNA Profiling of Murine Livers Following Acute Phase Intravenous Delivery of Ad5 Reveals Subsets of Hepatocyte and Kupffer Cell Regulated Genes.
Alba, R., Bradshaw, A.C., Parker, A.L., Bhella, D., Waddington, S.N., Nicklin, S.A., ...McVey, J.H. (2009). Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: Effect of mutagenesis on FX interactions and gene transfer. 114 965-971.
Greig, J.A., Buckley, S.M.K., Waddington, S.N., Parker, A.L., Bhella, D., Pink, R., ...McVey, J.H. (2009). Influence of Coagulation Factor X on In Vitro and In Vivo Gene Delivery by Adenovirus (Ad) 5, Ad35 and Chimeric Ad5/Ad35 Vectors. 17 (10), 1683-1691.
Greig, J.A., Buckley, S.M.K., Waddington, S.N., Parker, A.L., Bhella, D., Pink, R., ...McVey, J.H. (2009). Influence of Coagulation Factor X on In Vitro and In Vivo Gene Delivery by Adenovirus (Ad) 5, Ad35, and Chimeric Ad5/Ad35 Vectors. MOLECULAR THERAPY, 17 (10), 1683-1691. doi:10.1038/mt.2009.152
Greig, J.A., Buckley, S.M., Waddington, S.N., Parker, A.L., Bhella, D., Pink, R., ...McVey, J.H. (2009). Influence of coagulation factor x on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors.. MOLECULAR THERAPY, 17 (10), 1683-1691. doi:10.1038/mt.2009.152
Mattar, C.N., Dighe, N.M., Waddington, S.N., McIntosh, J., Biswas, A., Fisk, N.M., ...Chan, J. (2009). Long-Term Transgene Expression in New-Born Cynomolgus Macaques Following Intra-Uterine Gene Transfer of Self-Complementary AAV.
Ward, N.J., Apolonia, L., Cochrane, M., Buckley, S.M., Waddington, S.N., Nathwani, A.C., ...Thrasher, A.J. (2009). Nonintegrating Lentiviral Vectors for Treatment of Haemophilia B.
Ward, N.J., Apolonia, L., Cochrane, M., Buckley, S.M., Waddington, S.N., Nathwani, A.C., ...Thrasher, A.J. (2009). Nonintegrating Lentiviral Vectors for Treatment of Haemophilia B.
Pirianov, G., Waddington, S.N., Lindström, T.M., Terzidou, V., Mehmet, H., Bennett, P.R. (2009). The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse.. ENDOCRINOLOGY, 150 (2), 699-706. doi:10.1210/en.2008-1178
Pirianov, G., Waddington, S.N., Lindstrom, T.M., Terzidou, V., Mehmet, H., Bennett, P.R. (2009). The cyclopentone prostaglandin 15d-PGJ2 delays LPS-induced preterm delivery and reduces mortality in the new born mouse. 150 (2), 669-706.
Parker, A.L., Waddington, S.N., Buckley, S.M.K., Custers, J., Havenga, M.J.E., Rooijen, N.V., ...Baker, A.H. (2009). The effect of neutralising sera on factor X-mediated adenoviral serotype 5 gene transfer. 83 (1), 479-483.

2008

Waddington, S.N., Mcvey, J.H., Bhella, D., Parker, A.L., Barker, K., Atoda, K., ...Denby, L. (2008). A critical role for the adenovirus serotype 5 hexon in liver gene transfer.
Waddington, S.N., Mcvey, J.H., Bhella, D., Parker, A.L., Barker, K., Atoda, K., ...Denby, L. (2008). A critical role for the adenovirus serotype 5 hexon in liver gene transfer.
Waddington, S.N., McVey, J.H., Bhella, D., Parker, A.L., Barker, K., Atoda, H., ...Denby, L. (2008). Adenovirus serotype 5 hexon mediates liver gene transfer. CELL, 132 (3), 397-409. doi:10.1016/j.cell.2008.01.016
Waddington, S.N., McVey, J.H., Bhella, D., Parker, A.L., Barker, K., Atoda, H., ...Denby, L. (2008). Adenovirus serotype 5 hexon mediates liver gene transfer. CELL, 132 (3), 397-409. doi:10.1016/j.cell.2008.01.016
Parker, A.L., McVey, J.H., Waddington, S.N., Buckley, S.M.K., Francischetti, I.M.B., Monteiro, R.Q., ...Baker, A.H. (2008). An exosite within the human FX serine protease domain mediates cell transduction of AD5: FX complexes.
Parker, A.L., McVey, J.H., Waddington, S.N., Buckley, S.M.K., Francischetti, I.M.B., Monteiro, R.Q., ...Baker, A.H. (2008). An exosite within the human FX serine protease domain mediates cell transduction of AD5: FX complexes.
Rahim, A.A., Waddington, S.N., Wong, A.M.S., Ward, N.J., Elston, K.E., Buckley, S.M.K., ...Thrasher, A.J. (2008). Efficient gene delivery to the adult and fetal central nervous system using pseudotyped non-integrating lentiviral vectors.
Rahim, A.A., Waddington, S.N., Wong, A.M.S., Ward, N.J., Elston, K.E., Buckley, S.M.K., ...Thrasher, A.J. (2008). Efficient gene delivery to the adult and fetal central nervous system using pseudotyped non-integrating lentiviral vectors.
David, A.L., Torondel, B., Zachary, I., Wigley, V., Abi-Nader, K., Mehta, V., ...Rodeck, C.H. (2008). Erratum: Local delivery of VEGF adenovirus to the uterine artery increases vasorelaxation and uterine blood flow in the pregnant sheep (Gene Therapy (2008) vol. 15 (1344-1350) 10.1038/sj.gt.2008.102). Gene Therapy, 15 (20), 1410-. doi:10.1038/gt.2008.157
Greig, J.A., McVey, J.H., Waddington, S.N., Parker, A.L., Buckley, S.M.K., Havenga, M.J.E., ...Baker, A.H. (2008). Factor X enhances binding and transduction of human cancer cell lines by adenovirus (Ad) serotype 5 vectors but not by Ad35.
Waddington, S.N., Buckley, S.M.K., Coutelle, C. (2008). Fetal gene therapy. (June),
Waddington, S.N., Buckley, S.M.K., Coutelle, C. (2008). Fetal gene therapy: Intervention in utero. Biochemist, 30 (3), 7-9.
Waddington, S.N., Buckley, S.M.K., Coutelle, C. (2008). Fetal gene therapy: Intervention in utero. Biochemist, 30 (3), 7-9.
Crossley, R., Waddington, S.N., Howe, S., Buckley, S., Reynolds, L., Sheard, V., ...Mckay, T.R. (2008). Gene delivery of latency ablated TGF-beta 3 regulates dermal wound re-epithelialization in mice and reduces factors associated with scar tissue formation.
Tuddenham, E.G., Ingerslev, J., Sorensen, L.N., Christiansen, K., Mariani, G., Peyvandi, F., ...Chuah, M.K. (2008). Genetic aspects and research development in haemostasis. HAEMOPHILIA, 14 113-118. doi:10.1111/j.1365-2516.2008.01740.x
Tuddenham, E.G., Ingerslev, J., Norengaard Sorensen, L., Christiansen, K., Mariani, G., Peyvandi, F., ...Chuah, M.K. (2008). Genetic aspects and research development in haemostasis. 14 (s3), 113-118.
Tuddenham, E.G., Ingerslev, J., Sorensen, L.N., Christiansen, K., Mariani, G., Peyvandi, F., ...Chuah, M.K. (2008). Genetic aspects and research development in haemostasis. HAEMOPHILIA, 14 113-118. doi:10.1111/j.1365-2516.2008.01740.x
Waddington, S.N., Buckley, S.M.K., Nivsarkar, M.S., Coutelle, C. (2008). Immune responses after in utero and neonatal gene transfer. In Herzog, R.W. (Ed.), Gene Therapy Immunology. John Wiley & Sons Inc..
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Bergau, A., Themis, M., MacVinish, L.J., ...Coutelle, C. (2008). Intra-amniotic delivery of CFTR expressing adenovirus does not reverse Cystic Fibrosis phenotype in inbred CFTR-knockout mice.
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Bergau, A., Themis, M., MacVinish, L.J., ...Coutelle, C. (2008). Intra-amniotic delivery of CFTR expressing adenovirus does not reverse Cystic Fibrosis phenotype in inbred CFTR-knockout mice.
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Bergau, A., Themis, M., MacVinish, L.J., ...Coutelle, C. (2008). Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout mice.. MOLECULAR THERAPY, 16 (5), 819-824. doi:10.1038/mt.2008.26
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Bergau, A., Themis, M., MacVinish, L.J., ...Coutelle, C. (2008). Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout mice.. MOLECULAR THERAPY, 16 (5), 819-824. doi:10.1038/mt.2008.26
Buckley, S.M., Howe, S.J., Sheard, V., Ward, N.J., Coutelle, C., Thrasher, A.J., ...McKay, T.R. (2008). Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression. Gene Ther., 15 (16), 1167-1175.
Buckley, S.M., Howe, S.J., Sheard, V., Ward, N.J., Coutelle, C., Thrasher, A.J., ...McKay, T.R. (2008). Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression. Gene Ther., 15 (16), 1167-1175.
David, A.L., Torondel, B., Zachary, I., Wigley, V., Abi-Nader, K., Mehta, V., ...Rodeck, C.H. (2008). Local delivery of VEGF adenovirus to the uterine artery increases vasorelaxation and uterine blood flow in the pregnant sheep (vol 15, pg 1344, 2008).
David, A.L., Torondel, B., Zachary, I., Wigley, V., Abi Nader, K., Mehta, V., ...Rodeck, C.H. (2008). Local delivery of VEGF adenovirus to the uterine artery increases vasorelaxation and uterine blood flow in the pregnant sheep.. Gene Therapy, 15 1344-1350.
Buckley, S.M., Howe, S.J., Rahim, A.A., Buning, H., McIntosh, J., Wong, S.P., ...Coutelle, C. (2008). Luciferin Detection After Intranasal Vector Delivery Is Improved by Intranasal Rather Than Intraperitoneal Luciferin Administration.. Hum.Gene Ther., 19 (10), 1050-1056.
Buckley, S.M., Howe, S.J., Rahim, A.A., Buning, H., McIntosh, J., Wong, S.P., ...Coutelle, C. (2008). Luciferin Detection After Intranasal Vector Delivery Is Improved by Intranasal Rather Than Intraperitoneal Luciferin Administration.. Hum.Gene Ther., 19 (10), 1050-1056.
Buckley, S.M., Howe, S.J., Wong, S.P., Buning, H., McIntosh, J., Baker, A., ...McKay, T.R. (2008). Luciferin detection after intra-nasal vector delivery is improved by intra-nasal rather than intra-peritoneal luciferin administration.. Hum Gene Ther, doi:10.1089/hgt.2008.023
Ward, N.J., Apolonia, L., Fernandes, C., Waddington, S.N., Cochrane, M., Nathwani, A.C., ...Philpott, N.J. (2008). Non-integrating lentiviral vector pseudotypes for safer gene therapy.
Argyros, O., Wong, S.P., Niceta, M., Waddington, S.N., Howe, S.J., Coutelle, C., ...Harbottle, R.P. (2008). Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector. GENE THERAPY, 15 (24), 1593-1605. doi:10.1038/gt.2008.113
Argyros, O., Wong, S.P., Niceta, M., Waddington, S.N., Howe, S.J., Coutelle, C., ...Harbottle, R.P. (2008). Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector.. Gene Therapy, 15 (24), 1593-1605. doi:10.1038/gt.2008.113
Argyros, O., Wong, S.P., Nicetta, M., Waddington, S.N., Coutelle, C., Miller, A.D., Harbottle, R.P. (2008). Persistent episomal transgene expression in liver following hydrodynamic delivery of S/MAR-Containing plasmid DNA.
Thornhill, S., Grassman, E., Ulaganathan, M., Waddington, S.N., Howe, S.J., Van der Loo, H., ...Williams, D. (2008). Self-inactivating retroviral vectors for gene therapy of SCID-X1.

2007

Hibbitt, O.C., Harbottle, R.P., Waddington, S.N., Bursill, C.A., Coutelle, C., Channon, K.M., Wade-Martins, R. (2007). Delivery and long-term expression of a 135 kb LDLR genomic DNA locus in vivo by hydrodynamic tail vein injection. 9 (6), 488-497.
Waddington, S.N., Buckley, S.M., David, A.L., Peebles, D.M., Rodeck, C.H., Coutelle, C. (2007). Fetal gene transfer. Curr Opin Mol Ther, 9 432-438.
Waddington, S.N., Buckley, S.M., David, A.L., Peebles, D.M., Rodeck, C.H., Coutelle, C. (2007). Fetal gene transfer. Curr Opin Mol Ther, 9 432-438.
Parker, A.L., McVey, J.H., Doctor, J.H., Lopez-Franco, O., Waddington, S.N., Havenga, M.J.E., ...Baker, A.H. (2007). Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D. JOURNAL OF VIROLOGY, 81 (7), 3627-3631. doi:10.1128/JVI.02786-06
Apolonia, L., Waddington, S.N., Fernandes, C., Ward, N.J., Bouma, G., Blundell, M.P., ...Philpott, N.J. (2007). Stable Gene Transfer to Muscle Using Non-integrating Lentiviral Vectors. Mol Ther.,
Waddington, S.N., Parker, A.L., Havenga, M., Nicklin, S.A., Buckley, S.M., McVey, J.H., Baker, A.H. (2007). Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5.. Journal of Virology, 81 (17), 9568-9571. doi:10.1128/JVI.00663-07
Waddington, S.N., Parker, A.L., Havenga, M., Nicklin, S.A., Buckley, S.M., McVey, J.H., Baker, A.H. (2007). Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5.. Journal of Virology, 81 (17), 9568-9571. doi:10.1128/JVI.00663-07
Baker, A.H., Mcvey, J.H., Waddington, S.N., Di Paolo, N.C., Shayakhmetov, D.M. (2007). The influence of blood on in vivo adenovirus bio-distribution and transduction. MOLECULAR THERAPY, 15 (8), 1410-1416. doi:10.1038/sj.mt.6300206
Buckley, S.M.K., Howe, S.J., Thrasher, A., Baker, A.H., Mckay, T.R., Coutelle, C., Waddington, S. (2007). The route of luciferin administration is a critical determinant of detection of pulmonary and nasal luciferase expression by in vivo bioimaging.
Chan, J., Waddington, S.N., O'Donoghue, K., Kurata, H., Guillot, P.V., Gotherstrom, C., ...Fisk, N.M. (2007). Widespread distribution and muscle differentiation of human fetal mesenchymal stem cells after intrauterine transplantation in dystrophic mdx mouse. Stem Cells, 25 (4), 875-884.

2006

David, A.L.M., Peebles, D.M., Gregory, L., Waddington, S.N., Themis, M., WeiszB, R., ...C H, C. (2006). Clinically applicable procedure for gene delivery to fetal gut by ultrasound-guided gastric injection: toward prenatal prevention of early-onset intestinal diseases.. Human Gene Therapy, 17 (7), 767-769. doi:10.1089/hum.2006.17.767
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y., Al-Allaf, F., ...Holder, M.V. (2006). Erratum: "Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice" (Molecular Therapy (2005) vol. 12 (763-771) 10.1016/j.ymthe.2005.07.358). Molecular Therapy, 13 (4), 830-. doi:10.1016/j.ymthe.2005.10.003
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y., Al-Allaf, F., ...Holder, M.V. (2006). Erratum: "Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice" (Molecular Therapy (2005) vol. 12 (763-771) 10.1016/j.ymthe.2005.07.358). Molecular Therapy, 13 (4), 830-. doi:10.1016/j.ymthe.2005.10.003
Muhle, C., Neuner, A., Park, J., Pacho, F., Jiang, Q., Waddington, S.N., Schneider, H. (2006). Evaluation of prenatal intra-amniotic LAMB3 gene delivery in a mouse model of Herlitz disease. 13 (23), 1665-1676.
David, A.L., Rodeck, C.H. (2006). Gene Therapy. In van Vugt, J.M.G., Shulman, L.P. (Eds.), Prenatal Medicine. New York: Taylor & Francis.
Parker, A.L., Nicol, C.G., Waddington, S.N., Buckley, S.M., Shayakhmetov, D.M., Ni, S.H., ...Nicklin, S.A. (2006). Hepatic Tropism of Adenoviral Type 5 Vectors Can Be Mediated by Multiple Coagulation Factors.
David, A.L., Torondel, B., Zachary, I., Ramirez, M.J., Buckley, S.M., Cook, T., ...Peebles, D. (2006). Local delivery of adenovirus VEGF to the uterine arteries increases vessel relaxation and uterine artery blood flow in the sheep.
Parker, A.L., Waddington, S.N., Nicol, C.G., Shayakhmetov, D.M., Buckley, S.M., Denby, L., ...McVey, J.H. (2006). Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes. Blood, 108 (8), 2554-2561. doi:10.1182/blood-2006-04-008532
Parker, A.L., Waddington, S.N., Nicol, C.G., Shayakhmetov, D.M., Buckley, S.M., Denby, L., ...McVey, J.H. (2006). Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes. Blood, 108 (8), 2554-2561. doi:10.1182/blood-2006-04-008532
Parker, A.L., Waddington, S.N., Nicol, C.G., Shayakhmetov, D.M., Buckley, S.M.K., Denby, L., ...McVey, J.H. (2006). Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes in vitro and in vivo. 108 (8), 2554-2561.
Parker, A.L., Waddington, S.N., Nicol, C.G., Shayakhmetov, D.M., Buckley, S.M., Denby, L., ...McVey, J.H. (2006). Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes.. Blood, 108 (8), 2554-2561. doi:10.1182/blood-2006-04-008532
Parker, A.L., Waddington, S.N., Nicol, C.G., Shayakhmetov, D.M., Buckley, S.M., Denby, L., ...McVey, J.H. (2006). Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes.. Blood, 108 (8), 2554-2561. doi:10.1182/blood-2006-04-008532
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y., Al-Allaf, F., ...Holder, M.V. (2006). Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice (vol 12, pg 763, 2005). MOLECULAR THERAPY, 13 (4), 830. doi:10.1016/j.ymthe.2005.07.358
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y., Al-Allaf, F., ...Holder, M.V. (2006). Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice (vol 12, pg 763, 2005). MOLECULAR THERAPY, 13 (4), 830. doi:10.1016/j.ymthe.2005.07.358
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y.H., Al-Allaf, F., ...Holder, M. (2006). Oncogenesis following delivery of a non-primate lentiviral gene therapy vector to fetal mice.
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y.H., Al-Allaf, F., ...Holder, M. (2006). Oncogenesis following delivery of a non-primate lentiviral gene therapy vector to fetal mice.
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y., Al-Allaf, F., ...Holder, M. (2006). Oncogenesis Following Delivery of Lentiviral Vectors to Fetal and Neonatal Mice.
Bigger, B.W., Siapati, E.K., Mistry, A., Waddington, S.N., Nivsarkar, M.S., Jacobs, L., ...Kemball-Cook, G. (2006). Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX. 13 (2), 117-126.
Bigger, B.W., Siapati, E.K., Mistry, A., Waddington, S.N., Nivsarkar, M.S., Jacobs, L., ...Kemball-Cook, G. (2006). Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX. Gene Therapy, 13 (2), 117-126.
Sun, X.M., Eden, E.R., Waddington, S.N., Soutar, A.K. (2006). Recombineering of a bacterial artificial chromosome for generation of transgenic mice expressing myc-tagged wild type or mutant (D374Y) human PCSK9.
Nathwani, A.C., Gray, J.T., Ng, C.Y., Zhou, J., Spence, Y., Waddington, S.N., ...Boon-Spijker, M. (2006). Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver.. Blood, 107 (7), 2653-2661.
Thanou, M., Miller, A.D., Waddington, S. (2006). The impact of new genomic technologies: Gene Therapy. In Triggle, D.J., Taylor, J.B. (Eds.), Comprehensive Medicinal Chemistry II. Elsevier Ltd..

2005

Buckley, S.M.K., Waddington, S.N., Jezzard, S., Lawrence, L., Schneider, H., Themis, M., Coutelle, C. (2005). Factors influencing adenovirus-medated airway transduction in fetal mice. 12 (3), 484-492.
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Lawrence, L., Schneider, H., Holder, M.V., ...Coutelle, C. (2005). Factors influencing adenovirus-mediated airway transduction in fetal mice. MOLECULAR THERAPY, 12 (3), 484-492. doi:10.1016/j.ymthe.2005.02.020
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Lawrence, L., Schneider, H., Holder, M.V., ...Coutelle, C. (2005). Factors influencing adenovirus-mediated airway transduction in fetal mice. MOLECULAR THERAPY, 12 (3), 484-492. doi:10.1016/j.ymthe.2005.02.020
Coutelle, C., Themis, M., Waddington, S., Buckley, S., Gregory, L., Nivsarkar, M., ...Rodeck, C. (2005). Fetal gene therapy – first proofs of concept - some adverse effects. 12 (22), 1601-1607.
Coutelle, C., Themis, M., Waddington, S.N., Buckley, S.M., Gregory, L.G., Nivsarkar, M.S., ...Rodeck, C. (2005). Gene Therapy Progress and Prospects: Fetal gene therapy - first proofs of concept - some adverse effects. Gene Therapy, 12 1601-1607.
Coutelle, C., Themis, M., Waddington, S.N., Buckley, S.M.K., Gregory, L.G., Nivsarkar, M.S., ...Rodeck, C. (2005). Gene therapy progress and prospects: Fetal gene therapy - first proofs of concept - some adverse effects. GENE THERAPY, 12 (22), 1601-1607. doi:10.1038/sj.gt.3302632
Coutelle, C., Themis, M., Waddington, S.N., Buckley, S.M., Gregory, L.G., Nivsarkar, M.S., ...Rodeck, C. (2005). Gene Therapy Progress and Prospects: Fetal gene therapy - first proofs of concept - some adverse effects. Gene Therapy, 12 1601-1607.
Coutelle, C., Themis, M., Waddington, S.N., Buckley, S.M.K., Gregory, L.G., Nivsarkar, M.S., ...Rodeck, C. (2005). Gene therapy progress and prospects: Fetal gene therapy - first proofs of concept - some adverse effects. GENE THERAPY, 12 (22), 1601-1607. doi:10.1038/sj.gt.3302632
Waddington, S.N., Kramer, M.G., Hernandez-Alcoceba, R., Buckley, S.M.K., Themis, M., Coutelle, C., Prieto, J. (2005). In utero gene therapy: Current challenges and perspectives. MOLECULAR THERAPY, 11 (5), 661-676. doi:10.1016/j.ymthe.2005.01.015
Waddington, S.N., Kramer, M.G., Hernandez-Alcoceba, R., Buckley, S.M.K., Themis, M., Coutelle, C., Prieto, J. (2005). In Utero Gene Therapy: Current Challenges And Perspectives. 11 (5), 661-676.
Waddington, S.N., Kramer, M.G., Hernandez-Alcoceba, R., Buckley, S.M.K., Themis, M., Coutelle, C., Prieto, J. (2005). In utero gene therapy: Current challenges and perspectives. MOLECULAR THERAPY, 11 (5), 661-676. doi:10.1016/j.ymthe.2005.01.015
Jakob, M., Mühle, C., Park, J., Weiß, S., Waddington, S., Schneider, H. (2005). No evidence for germ-line transmission following prenatal and early postnatal AAV-mediated gene delivery. 7 (6), 630-637.
Jakob, M., Muhle, C., Park, J., Weiss, S., Waddington, S., Schneider, H. (2005). No evidence for germ-tine transmission following prenatal and early postnatal AAV-mediated gene delivery. JOURNAL OF GENE MEDICINE, 7 (5), 630-637. doi:10.1002/jgm.718
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y.H., Al-Allaf, F., ...Holder, M.V. (2005). Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice. MOLECULAR THERAPY, 12 (4), 763-771. doi:10.1016/j.ymthe.2005.07.358
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y.H., Al-Allaf, F., ...Holder, M.V. (2005). Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice. MOLECULAR THERAPY, 12 (4), 763-771. doi:10.1016/j.ymthe.2005.07.358
Themis, M., Waddington, S.N., Schmitt, M., Von Kalle, C., Wang, Y., Al-Allaf, F., ...Holder, M.V. (2005). Oncogenesis following delivery of a non-primate lentiviral gene therapy vector to fetal and neonatal mice. 12 (4), 763-771.
Weisz, B., David, A.L., Gregory, L.G., Perocheau, D., Ruthe, A., Waddington, S.N., ...Rodeck, C.H. (2005). Targeting the respiratory muscles of fetal sheep for prenatal gene therapy for Duchenne muscular dystrophy.. American Journal of Obstetrics and Gynecology, 193 (3pt2), 1105-1109. doi:10.1016/j.ajog.2005.06.077
Themis, M., Bennett, P.R., Mehmet, H., Waddington, S.N., Buckley, S.M. (2005). The development of a mouse model to study the effect of uterine infection on preterm labour and fetal outcome..
Themis, M., Bennett, P.R., Mehmet, H., Waddington, S.N., Buckley, S.M. (2005). The development of a mouse model to study the effect of uterine infection on preterm labour and fetal outcome..

2004

Holder, M.V., Waddington, S.N., Gregory, L.G., Kramer, M.G., Prieto, J., Mitrophanous, K., ...Bigger, B.W. (2004). Comparison of gene expression from liver specific promoter/enhancer combinations in the context of a lentiviral backbone.
Hoare, J., Waddington, S., Thomas, H.C., Coutelle, C., McGarvey, M.J. (2004). Complement inhibition rescued mice allowing observation of transgene expression following intraportal delivery of baculovirus in mice. 7 (3), 325-333.
Waddington, S.N., Kennea, N.L., Buckley, S.M.K., Gregory, L.G., Themis, M., Coutelle, C. (2004). Fetal and neonatal gene therapy: benefits and pitfalls. 11 (S1), 92-97.
Waddington, S.N., Kennea, N.L., Buckley, S.M.K., Gregory, L.G., Themis, M., Coutelle, C. (2004). Fetal and neonatal gene therapy: benefits and pitfalls.
Waddington, S.N., Kennea, N.L., Buckley, S.M.K., Gregory, L.G., Themis, M., Coutelle, C. (2004). Fetal and neonatal gene therapy: benefits and pitfalls.
Gregory, L.G., Waddington, S.N., Holder, M.V., Mitrophanous, K.A., Buckley, S.M.K., Mosley, K.L., ...Lawrence, L. (2004). Highly efficient EIAV-mediated in utero gene transfer and expression in the major muscle groups affected by Duchenne muscular dystrophy. GENE THERAPY, 11 (14), 1117-1125. doi:10.1038/sj.gt.3302268
Gregory, L.G., Waddington, S.N., Holder, M.V., Mitrophanous, K.A., Buckley, S.M.K., Mosley, K.L., ...Lawrence, L. (2004). Highly efficient EIAV-mediated in utero gene transfer and expression in the major muscle groups affected by Duchenne muscular dystrophy. GENE THERAPY, 11 (14), 1117-1125. doi:10.1038/sj.gt.3302268
Gregory, L.G., Waddington, S.N., Holder, M.V., Mitrophanous, K.A., Buckley, S.M.K., Mosley, K.M., ...Lawrence, L. (2004). Highly efficient EIAV-mediated in utero gene transfer and expression in the major muscle groups affected by Duchenne Muscular Dystrophy.. 11 (14), 1117-1125.
Waddington, S.N., Nivsarkar, M., Mistry, A., Buckley, S.M.K., Kemball-Cook, G., Mosley, K.L., ...Brittan, M. (2004). Permanent phenotypic correction of Haemophilia B in immunocompetent mice by prenatal gene therapy.
Waddington, S.N., Nivsarkar, M.S., Mistry, A.R., Buckley, S.M.K., Kemball-Cook, G., Mosley, K.L., ...Brittan, M. (2004). Permanent phenotypic correction of haemophilia B in immunocompetent mice by prenatal gene therapy.
Waddington, S.N., Nivsarkar, M., Mistry, A., Buckley, S.M.K., Kemball-Cook, G., Mosley, K.L., ...Brittan, M. (2004). Permanent phenotypic correction of Haemophilia B in immunocompetent mice by prenatal gene therapy.
Waddington, S.N., Nivsarkar, M.S., Mistry, A.R., Buckley, S.M.K., Kemball-Cook, G., Mosley, K.L., ...Brittan, M. (2004). Permanent phenotypic correction of haemophilia B in immunocompetent mice by prenatal gene therapy.
Waddington, S.N., Nivsarkar, M.S., Mistry, A.R., Buckley, S.M., Kemball-Cook, G., Mosley, K.L., ...Brittan, M. (2004). Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy.. Blood, 104 (9), 2714-2721. doi:10.1182/blood-2004-02-0627
Waddington, S.N., Nivsarkar, M.S., Mistry, A.R., Buckley, S.M., Kemball-Cook, G., Mosley, K.L., ...Brittan, M. (2004). Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy.. Blood, 104 (9), 2714-2721. doi:10.1182/blood-2004-02-0627
Gregory, L.G., Waddington, S.N., Holder, M., Mitrophanous, K.A., Buckley, S.M.K., Ellard, F.M., ...Kingsman, S. (2004). Pseudotyped lentiviral vectors: Toward an applicability for in utero treatment of Duchenne Muscular Dystrophy.
Gregory, L.G., Waddington, S.N., Holder, M., Mitrophanous, K.A., Buckley, S.M.K., Ellard, F.M., ...Kingsman, S. (2004). Pseudotyped lentiviral vectors: Toward an applicability for in utero treatment of Duchenne Muscular Dystrophy.
Waddington, S.N., Buckley, S.M.K., Bernloehr, C., Bossow, S., Ungerechts, G., Cook, T., ...Neubert, W.J. (2004). Reduced toxicity of F-deficient Sendai virus vector in the mouse fetus. GENE THERAPY, 11 (7), 599-608. doi:10.1038/sj.gt.3302205
Waddington, S.N., Buckley, S.M.K., Bernloehr, C., Bossow, S., Ungerechts, G., Cook, T., ...Neubert, W.J. (2004). Reduced toxicity of F-deficient Sendai virus vector in the mouse fetus. 11 (7), 599-608.
Waddington, S.N., Buckley, S.M.K., Bernloehr, C., Bossow, S., Ungerechts, G., Cook, T., ...Neubert, W.J. (2004). Reduced toxicity of F-deficient Sendai virus vector in the mouse fetus. GENE THERAPY, 11 (7), 599-608. doi:10.1038/sj.gt.3302205
Nivsarkar, M.S., Nathwani, A., Mosley, K., Davies, N., Gregory, L.G., David, A.L., ...Waddington, S.N. (2004). Testosterone induced increase in transgene expression in vivo using Adenoviral Gene Delivery Vectors.
Themis, M., Gregory, L.G., Waddington, S.N., Holder, M.V., Mitrophanous, K.A., Buckley, S.M.K., ...Radcliff, P. (2004). The fetal approach: A novel therapy for the treatment of musculo-skeletal disease.
Themis, M., Gregory, L.G., Waddington, S.N., Holder, M.V., Mitrophanous, K.A., Buckley, S.M.K., ...Radcliff, P. (2004). The fetal approach: A novel therapy for the treatment of musculo-skeletal disease.
Peebles, D., Gregory, L.G., David, A., Themis, M., Waddington, S.N., Knapton, H.J., ...Nivsarkar, M. (2004). Widespread and efficient marker gene expression in the airway epithelia of fetal sheep after minimally invasive tracheal application of recombinant adenovirus in utero. GENE THERAPY, 11 (1), 70-78. doi:10.1038/sj.gt.3302130
Peebles, D.M., Gregory, L.G., David, A., Themis, M., Waddington, S.N., Knapton, H.J., ...Nivsarkar, M. (2004). Widespread and efficient marker gene expression in the airway epithelia of fetal sheep after minimally invasive tracheal application of recombinant adenovirus in utero.. Gene Therapy, 11 70-78. doi:10.1038/sj.gt.3302130
Peebles, D., Gregory, L.G., David, A., Themis, M., Waddington, S., Knapton, H.J., ...Nivsarkar, M. (2004). Widespread marker gene expression in the airway epithelia of fetal sheep after tracheal application of recombinant adenovirus in utero. 11 (1), 70-78.

2003

Waddington, S.N., Buckley, S.M.K., Cook, T., Gregory, L., Rahim, A., Nivsarkar, M., ...Lauer, U.M. (2003). Fetal gene delivery using first and second generation Sendai virus.
Waddington, S.N., Buckley, S.M.K., Cook, T., Gregory, L., Rahim, A., Nivsarkar, M., ...Lauer, U.M. (2003). Fetal gene delivery using first and second generation Sendai virus.
Waddington, S.N., Buckley, S.M.K., Nivsarkar, M., Jezzard, S., Schneider, H., Dahse, T., ...Dallman, M.J. (2003). In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor. BLOOD, 101 (4), 1359-1366. doi:10.1182/blood-2002-03-0779
Waddington, S.N., Buckley, S.M.K., Nivsarkar, M., Jezzard, S., Schneider, H., Dahse, T., ...Dallman, M.J. (2003). In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor. BLOOD, 101 (4), 1359-1366. doi:10.1182/blood-2002-03-0779
Waddington, S.N., Buckley, S.M., Nivsarkar, M., Jezzard, S., Schneider, H., Dahse, T., ...Dallman, M.J. (2003). In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor.. Blood, 101 (4), 1359-1366. doi:10.1182/blood-2002-03-0779
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Themis, M., Colledge, W.H., Coutelle, C. (2003). Intra-amniotic application of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred Cftr-knockout mice.
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Themis, M., Colledge, W.H., Coutelle, C. (2003). Intra-amniotic application of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred Cftr-knockout mice.
Waddington, S.N., Mitrophanous, K.A., Ellard, F.M., Buckley, S.M.K., Nivsarkar, M., Lawrence, L., ...Kingsman, S.M. (2003). Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice. GENE THERAPY, 10 (15), 1234-1240. doi:10.1038/sj.gt.3301991
Waddington, S.N., Mitrophanous, K.A., Ellard, F., Buckley, S.M.K., Nivsarkar, M., Lawrence, L., ...Kingsman, S. (2003). Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice. 10 (15), 1234-1240.
Waddington, S.N., Mitrophanous, K.A., Ellard, F.M., Buckley, S.M.K., Nivsarkar, M., Lawrence, L., ...Kingsman, S.M. (2003). Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice. GENE THERAPY, 10 (15), 1234-1240. doi:10.1038/sj.gt.3301991
David, A.L., Themis, M., Waddington, S.N., Gregory, L., Buckley, S.M.K., Nivsarkar, M., ...Coutelle, C. (2003). The current status and future directions of fetal gene therapy. 7 181-209.
Coutelle, C., Themis, M., Waddington, S., Gregory, L., Nivsarkar, M., Buckley, S., ...David, A. (2003). The hopes and fears of in utero gene therapy for genetic disease - a review. Placenta, 24 S114-S121.
Coutelle, C., Themis, M., Waddington, S., Gregory, L., Nivsarkar, M., Buckley, S., ...David, A. (2003). The hopes and fears of in utero gene therapy for genetic disease - A review. Placenta, 24 (SUPPL. B), doi:10.1016/S0143-4004(03)00140-1
Coutelle, C., Themis, M., Waddington, S., Gregory, L., Nivsarkar, M., Buckley, S., ...David, A. (2003). The hopes and fears of in utero gene therapy for genetic disease - A review. Placenta, 24 (SUPPL. B), doi:10.1016/S0143-4004(03)00140-1
Coutelle, C., Themis, M., Waddington, S., Gregory, L., Nivsarkar, M., Buckley, S., ...David, A. (2003). The hopes and fears of in utero gene therapy for genetic disease--a review. 24 Suppl B S114-S121.
David, A.L.M., Cook, T., Waddington, S., Peebles, D., Nivsarkar, M., Knapton, H., ...Schneider, H. (2003). Ultrasound guided percutaneous delivery of adenoviral vectors encoding the beta-galactosidase and human factor IX genes to early gestation fetal sheep in utero. Human Gene Therapy, 14 353-364. doi:10.1089/104303403321208952
David, A., Cook, T., Waddington, S., Peebles, D., Nivsarkar, M., Knapton, H., ...Schneider, H. (2003). Ultrasound guided percutaneous delivery of adenoviral vectors encoding the beta-galactosidase and human factor IX genes to early gestation fetal sheep in utero. 14 (4), 353-364.
Gregory, L.G., Peebles, D., David, A., Themis, M., Waddington, S.N., Knapton, H.J., ...Nivsarkar, M. (2003). Widespread and efficient adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in adult mice and fetal sheep after minimally invasive tracheal application.

2002

Waddington, S.N. (2002). Arginase in glomerulonephritis. 61 (3), 876-881.
Schneider, H., Mühle, C., Douar, A.M., Waddington, S., Jiang, Q., Mark, K.V.D., ...Rascher, W. (2002). Sustained delivery of therapeutic concentrations of human clotting factor IX - a comparison of adenoviral and AAV vectors administered in utero. 4 46-53.

2000

Waddington, S.N., Cattell, V. (2000). Arginase in glomerulonephritis.. EXPERIMENTAL NEPHROLOGY, 8 (3), 128-134.

1999

Waddington, S.N., Cattell, V. (1999). Arginase in glomerulonephritis. 2000 (8), 128-134.
Waddington, S.N., Mosley, K., Cattell, V. (1999). Induced nitric oxide (NO) synthesis in heterologous nephrotoxic nephritis; effects of selective inhibition in neutrophil-dependent glomerulonephritis. 118 (2), 309-314.
Mosley, K., Waddington, S.N., Ebrahim, H., Cook, T., Cattell, V. (1999). Inducible nitric oxide synthase induction in thy 1 glomerulonephritis is complement and reactive oxygen species dependent. 7 (1), 26-34.

1998

Cattell, V., Cook, H.T., Ebrahim, H., Waddington, S.N., Wei, X., Assman, K.J.M., Liew, F.Y. (1998). Anti-GBM glomerulonephritis in mice lacking nitric oxide synthase type 2. 53 932-936.
Waddington, S.N., Tam, F.W.K., Cook, H.T., Cattell, V. (1998). Arginase activity is modulated by IL-4 and HOArg in nephritic glomeruli and mesangial cells. 274 (3), F473-F480.
Waddington, S.N., Tam, F.W.K., Cook, H.T., Cattell, V. (1998). Arginase activity is modulated by IL-4 and HOArg in nephritic glomeruli and mesangial cells. American Journal of Physiology - Renal Physiology, 274 (3 43-3),
Waddington, S.N., Tam, F.W., Cook, H.T., Cattell, V. (1998). Arginase activity is modulated by IL-4 and HOArg in nephritic glomeruli and mesangial cells.. The American journal of physiology, 274 (3), F473-F480. doi:10.1152/ajprenal.1998.274.3.f473
Waddington, S.N., Mosley, K., Cook, H.T., Tam, F.W.K., Cattell, V. (1998). Arginase AI is upregulated in acute immune complex-induced inflammation. 247 84-87.

1996

Waddington, S., Cook, H.T., Reaveley, D., Jansen, A., Cattell, V. (1996). L-Arginine depletion inhibits glomerular nitric oxide synthesis and exacerbates rat nephrotoxic nephritis.. 49 1090-1096.

1991

Elliott, C.J.H., Kemenes, G., Waddington, S. (1991). The modulatory peptide SCPb inhibits feeding in the mollusc Lymnaea stagnalis. 100C (3), 615-618.
ELLIOTT, C.J.H., KEMENES, G., WADDINGTON, S. (1991). THE MODULATORY PEPTIDE SCPB INHIBITS FEEDING IN THE MOLLUSK, LYMNAEA-STAGNALIS. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, 100 (3), 615-618. doi:10.1016/0742-8413(91)90049-Y

Publications without a recorded date

Baruteau, J.C.(n.d.).A gene therapy approach for Argininosuccinic aciduria. (Doctoral Dissertation). University College London.